(S)-Warfarin, also known as (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone, is a cosmetic ingredient commonly used in skincare products for its anticoagulant properties. It works by inhibiting the synthesis of vitamin K-dependent clotting factors, which can help reduce the appearance of dark circles and puffiness around the eyes. Additionally, (S)-Warfarin has been shown to have antioxidant and anti-inflammatory effects, making it a versatile ingredient for a variety of cosmetic formulations. However, it should be used with caution and under the guidance of a healthcare professional due to its potential for interactions with other medications.
INCI name: (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone Common terms: (S)-Warfarin, Warfarin
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone is a type of flavonoid that is commonly used in cosmetic formulations due to its antioxidant and anti-inflammatory properties. It helps to protect the skin from damage caused by free radicals and environmental stressors, while also reducing inflammation and redness. Additionally, this ingredient has been shown to improve skin elasticity and firmness, making it a popular choice for anti-aging products. (S)-Warfarin, on the other hand, is not typically used in cosmetic formulations. It is a medication that is commonly used as a blood thinner to prevent blood clots and reduce the risk of stroke or heart attack. While it may have some potential benefits for the skin, it is not considered a safe or effective ingredient for use in cosmetics.
(S)-Warfarin works by inhibiting the synthesis of vitamin K-dependent clotting factors in the liver. Its physical properties allow it to bind to the active site of the enzyme vitamin K epoxide reductase, which is responsible for converting vitamin K epoxide to its active form. By binding to this enzyme, (S)-Warfarin prevents the conversion of vitamin K epoxide to its active form, thereby inhibiting the synthesis of clotting factors and preventing blood clots from forming.
There are no skincare benefits associated with (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone or (S)-Warfarin. These ingredients are primarily used as anticoagulants in medicine.
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone, also known as Troxerutin, is a flavonoid that is commonly used in dietary supplements and medications. While it is generally considered safe, there are some potential side effects and interactions that should be considered. One possible side effect of Troxerutin is gastrointestinal upset, including nausea, vomiting, and diarrhea. Some people may also experience headaches or dizziness. These side effects are generally mild and go away on their own, but if they persist or become severe, it is important to seek medical attention. Troxerutin may also interact with other medications or supplements. For example, it may increase the effects of (S)-Warfarin, a blood thinner, which could increase the risk of bleeding. People taking (S)-Warfarin should talk to their doctor before taking Troxerutin or any other supplements. Additionally, some people may be sensitive or allergic to Troxerutin. Symptoms of an allergic reaction may include hives, itching, swelling, or difficulty breathing. If you experience any of these symptoms after taking Troxerutin, stop using it immediately and seek medical attention. Overall, Troxerutin is a safe and effective ingredient when used as directed. However, it is important to be aware of potential side effects and interactions, and to talk to your doctor before taking any new supplements or medications.
(S)-Warfarin is a synthetic ingredient that was first developed in the 1940s as a rat poison. It is derived from the natural compound coumarin, which is found in many plants such as sweet clover and tonka beans. The processing pathway for (S)-Warfarin involves several steps, including the synthesis of coumarin and the addition of various chemical groups to create the final product. The resulting compound is a potent anticoagulant that is used to prevent blood clots in humans and animals.
According to the Environmental Working Group's Skin Deep database, (S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone has a low hazard score of 1 out of 10, indicating that it is considered safe for use in cosmetics and personal care products. However, (S)-Warfarin has a much higher hazard score of 7 out of 10, indicating that it may pose a moderate risk to human health and should be used with caution. Other sources, such as the National Institute for Occupational Safety and Health (NIOSH), also classify (S)-Warfarin as a hazardous substance due to its potential to cause harm through skin contact, inhalation, or ingestion. Overall, it is important to carefully consider the safety ratings of any chemical or ingredient before using it in personal care or other products.
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone, also known as coumarin, is a naturally occurring compound found in many plants, including cinnamon, tonka beans, and sweet clover. While coumarin itself is not harmful, it can be converted into a toxic substance called dicoumarol, which can cause bleeding disorders in animals and humans. In terms of environmental impact, the cultivation of plants that contain coumarin can have both positive and negative effects. On the one hand, these plants can provide important ecosystem services, such as soil conservation and carbon sequestration. On the other hand, the use of pesticides and other chemicals in their cultivation can have negative impacts on soil and water quality, as well as on the health of farm workers and nearby communities. As for ethical sourcing practices, it is important to ensure that coumarin-containing plants are grown and harvested in a sustainable and socially responsible manner. This may involve working with local communities to develop fair trade agreements, promoting organic farming practices, and supporting initiatives that protect biodiversity and natural habitats. (S)-Warfarin, on the other hand, is a synthetic derivative of coumarin that is used as an anticoagulant medication. While it has been widely prescribed for decades, its use has been controversial due to its potential for serious side effects, including bleeding and hemorrhage. In terms of environmental impact, the production and disposal of (S)-warfarin can have negative effects on soil and water quality, as well as on the health of wildlife and humans. Additionally, the use of (S)-warfarin in agriculture and pest control can lead to the development of resistant strains of pests and contribute to the decline of beneficial species, such as pollinators. In terms of ethical sourcing practices, it is important to ensure that (S)-warfarin is produced and used in a responsible and sustainable manner. This may involve promoting alternative methods of pest control, such as integrated pest management, and supporting initiatives that promote the safe disposal of unused medications. Additionally, efforts should be made to ensure that (S)-warfarin is only prescribed when necessary and that patients are properly monitored for potential side effects.
In conclusion, (S)-Warfarin is a potent anticoagulant that functions by inhibiting vitamin K-dependent clotting factors. While it has numerous benefits in preventing blood clots and reducing the risk of stroke, it also has potential negative side effects such as bleeding and drug interactions. It is primarily sourced from synthetic production and is considered safe when used as directed. However, its sustainability is questionable due to the environmental impact of its production. Overall, (S)-Warfarin remains an important medication in the treatment and prevention of thromboembolic disorders, but its use should be carefully monitored by healthcare professionals.
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