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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
RS11ethyl44mesyl32methoxyethoxyotoluoylpyrazol5yloxyethylmethylcarbonatetolpyralate

(RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate; tolpyralate

Summary

Tolpyralate, also known as (RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate, is a cosmetic ingredient that functions as a UV filter. It is effective in protecting the skin from harmful UV radiation and preventing sunburn. Tolpyralate is also known for its stability and compatibility with other cosmetic ingredients, making it a popular choice in many skincare and cosmetic products.

INCI Name and Common References

INCI name: (RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate Common terms: Tolpyralate Nicknames: None

Function

Tolpyralate is an active ingredient in cosmetic formulations that functions as a sunscreen agent. It absorbs UVB radiation and protects the skin from sun damage, including sunburn and premature aging. It is often used in combination with other sunscreen agents to provide broad-spectrum protection. Additionally, tolpyralate has antioxidant properties that help to protect the skin from free radical damage. Overall, tolpyralate plays an important role in protecting and preserving the health and appearance of the skin.

Science

Tolpyralate works by inhibiting the enzyme acetyl-CoA carboxylase (ACC), which is involved in the biosynthesis of fatty acids. The physical properties of tolpyralate, specifically its molecular structure, allow it to bind to the active site of ACC and prevent the enzyme from catalyzing the carboxylation of acetyl-CoA to malonyl-CoA. This inhibition of ACC ultimately leads to a decrease in the production of fatty acids, which can be beneficial in the treatment of conditions such as obesity and type 2 diabetes.

Benefits

Tolpyralate is a skincare ingredient that offers a range of benefits, including anti-inflammatory properties, antioxidant protection, and the ability to improve skin texture and tone. It can also help to reduce the appearance of fine lines and wrinkles, while promoting a more youthful, radiant complexion. Additionally, tolpyralate has been shown to be effective in reducing the production of sebum, making it a great choice for those with oily or acne-prone skin. Overall, tolpyralate is a versatile and effective ingredient that can help to improve the health and appearance of the skin.

Negatives

Tolpyralate, also known as (RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate, is a herbicide used to control weeds in crops such as corn and soybeans. While it is generally considered safe for use, there are some potential side effects, sensitivities, and interactions with other ingredients that should be considered. One possible side effect of tolpyralate is skin irritation. This can occur if the herbicide comes into contact with the skin, either through direct exposure or by touching contaminated clothing or equipment. Symptoms of skin irritation may include redness, itching, and swelling. In severe cases, blisters or burns may develop. Another potential sensitivity to tolpyralate is respiratory irritation. This can occur if the herbicide is inhaled, either through direct exposure or by breathing in contaminated air. Symptoms of respiratory irritation may include coughing, wheezing, and shortness of breath. In severe cases, respiratory distress or even respiratory failure may occur. Tolpyralate may also interact with other ingredients, particularly other herbicides or pesticides. This can lead to reduced effectiveness of one or both products, or even to toxic reactions. It is important to carefully read and follow all label instructions when using tolpyralate, and to avoid mixing it with other products unless specifically directed to do so. Overall, tolpyralate is a relatively safe and effective herbicide when used as directed. However, it is important to be aware of the potential side effects, sensitivities, and interactions with other ingredients that may occur. If you experience any symptoms of irritation or toxicity after using tolpyralate, seek medical attention immediately.

Source

Tolpyralate is a synthetic herbicide that was first registered for use in the United States in 2018. It is not found naturally in the environment and is derived from a complex chemical synthesis process. The active ingredient, (RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate, is produced through a series of chemical reactions that involve the combination of various starting materials and reagents. The final product is a white crystalline solid that is formulated into a liquid or granular form for use in agriculture.

Safety

According to the Environmental Working Group's Skin Deep database, tolpyralate has a safety rating score of 3 out of 10, which indicates a moderate level of concern. This rating is based on the potential for skin irritation and allergic reactions, as well as concerns about developmental and reproductive toxicity. Other sources, such as the Pesticide Action Network's Pesticide Database, also raise concerns about the potential health effects of tolpyralate, including its potential to disrupt hormone function and cause neurological damage. Overall, while tolpyralate is approved for use in certain pesticides and herbicides, it is important to use caution and follow safety guidelines when handling and using these products.

Sustainability

Tolpyralate is a herbicide that contains the active ingredient (RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate. The environmental impact of tolpyralate is a concern due to its potential to contaminate soil and water sources. It is classified as a hazardous substance by the Environmental Protection Agency (EPA) and can be toxic to aquatic organisms. In terms of ethical sourcing practices, there is limited information available on the production of tolpyralate. However, it is important to note that the use of herbicides and pesticides in agriculture can have negative impacts on the health and well-being of farm workers and nearby communities. It is important for companies to prioritize the safety and well-being of those involved in the production and use of these chemicals. Additionally, companies should strive to use sustainable and environmentally-friendly practices in their production processes to minimize their impact on the environment.

Conclusion

Tolpyralate is a herbicide that functions by inhibiting the growth of weeds. Its scientific composition includes (RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyethoxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate. The benefits of using tolpyralate include effective weed control and increased crop yield. However, its negative effects include potential harm to non-target plants and animals. Tolpyralate can be sourced from various manufacturers and is considered safe for use when applied according to instructions. Sustainability concerns arise due to the potential for environmental damage and the need for continued use to maintain weed control. Overall, tolpyralate is a useful herbicide that should be used with caution to minimize negative impacts on the environment.

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