MitoSkin

Longevity Lotion

Sun Protecting

Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
Carnitine

Carnitine

Summary

Carnitine is a naturally occurring amino acid derivative that plays a crucial role in energy metabolism. As a cosmetic ingredient, it has been shown to improve skin texture and firmness, reduce the appearance of fine lines and wrinkles, and enhance skin hydration. Carnitine also has antioxidant properties, which can help protect the skin from environmental stressors and premature aging. Its ability to promote cellular energy production makes it a valuable addition to anti-aging and revitalizing skincare formulations. Overall, carnitine is a versatile and effective ingredient that can benefit a wide range of cosmetic products.

INCI Name and Common References

International Nomenclature of Cosmetic Ingredients name: L-Carnitine Common terms: Carnitine Nicknames: None

Function

Carnitine is a naturally occurring amino acid that plays a vital role in cosmetic formulations. It is commonly used in skincare products due to its ability to boost cellular energy production and promote healthy skin cell turnover. Carnitine helps to improve skin texture and tone, reduce the appearance of fine lines and wrinkles, and enhance overall skin radiance. Additionally, it has antioxidant properties that protect the skin from environmental stressors and free radical damage. Carnitine is often found in anti-aging creams, serums, and lotions, as well as in hair care products to promote healthy hair growth and prevent hair loss.

Science

Carnitine is a naturally occurring amino acid derivative that plays a crucial role in the transportation of fatty acids into the mitochondria, the energy-producing organelles in cells. Its physical properties include a hydrophilic (water-loving) head and a hydrophobic (water-fearing) tail, which allows it to bind to fatty acids and shuttle them across the mitochondrial membrane. Once inside the mitochondria, carnitine is converted into acetyl-CoA, which is then used in the Krebs cycle to produce ATP, the primary energy source for cells. In summary, carnitine works by facilitating the transport of fatty acids into the mitochondria, where they can be metabolized to produce energy.

Benefits

Carnitine is a naturally occurring amino acid that has been found to have several skincare benefits. Some of the highlights include: 1. Reducing inflammation: Carnitine has anti-inflammatory properties that can help soothe irritated skin and reduce redness. 2. Improving skin texture: Carnitine can help improve skin texture by increasing cell turnover and promoting the growth of new skin cells. 3. Fighting acne: Carnitine has been shown to have antibacterial properties that can help fight acne-causing bacteria. 4. Boosting hydration: Carnitine can help improve skin hydration by increasing the production of natural moisturizing factors in the skin. 5. Protecting against UV damage: Carnitine has been found to have antioxidant properties that can help protect the skin against damage from UV radiation. Overall, carnitine is a versatile ingredient that can provide a range of skincare benefits, making it a valuable addition to any skincare routine.

Negatives

Carnitine is generally considered safe when taken in recommended doses. However, some people may experience side effects such as nausea, vomiting, diarrhea, stomach cramps, and a fishy odor in sweat, breath, and urine. These side effects are usually mild and go away on their own. People with certain medical conditions, such as kidney disease, liver disease, or peripheral vascular disease, should avoid taking carnitine supplements without consulting their healthcare provider. Carnitine may also interact with certain medications, including blood thinners, thyroid hormones, and valproic acid. Individuals with a history of seizures or bipolar disorder should also use caution when taking carnitine supplements, as it may worsen these conditions. Additionally, some people may be sensitive to carnitine and experience an allergic reaction, such as hives, itching, or difficulty breathing. It is important to note that carnitine is often added to energy drinks and other supplements, which may contain other ingredients that can interact with carnitine or cause additional side effects. It is always best to consult with a healthcare provider before taking any new supplement or medication.

Source

Carnitine is a naturally occurring amino acid derivative that is found in meat and dairy products. It is also synthesized in the liver and kidneys from the amino acids lysine and methionine. Carnitine is commonly used as a dietary supplement to support weight loss and improve athletic performance. The processing pathway of carnitine involves several steps. First, the amino acids lysine and methionine are converted into gamma-butyrobetaine by enzymes in the liver and kidneys. Gamma-butyrobetaine is then converted into carnitine by an enzyme called gamma-butyrobetaine hydroxylase. The final step involves transporting carnitine to the muscles and other tissues where it is needed for energy production. While carnitine can be obtained naturally from food sources, it is also available in synthetic form as a dietary supplement. However, excessive intake of carnitine supplements can lead to side effects such as nausea, vomiting, and diarrhea. It is important to consult with a healthcare professional before taking any dietary supplements.

Safety

Carnitine has a low safety rating score according to the EWG Skin Deep database. It has been rated as a 3 out of 10, which means it has a moderate level of concern for potential health hazards. However, other sources such as the National Institutes of Health (NIH) have deemed carnitine as safe for most people when taken in recommended doses. It is important to note that individual sensitivities and allergies may vary, and it is always recommended to consult with a healthcare professional before taking any supplements or making significant changes to your diet.

Sustainability

Carnitine is an amino acid that is naturally produced in the body and is also found in certain foods such as meat, fish, and dairy products. It is commonly used as a dietary supplement to improve athletic performance and aid in weight loss. In terms of environmental impact, the production of carnitine supplements can have negative effects on the environment. The manufacturing process often involves the use of chemicals and energy-intensive processes that contribute to greenhouse gas emissions and pollution. Additionally, the production of animal-based sources of carnitine, such as meat and dairy products, can have a significant impact on the environment due to the large amounts of resources required to raise and feed livestock. When it comes to ethical sourcing practices, the use of animal-based sources of carnitine raises concerns about animal welfare. Many factory farms use inhumane practices such as overcrowding, confinement, and the use of antibiotics and hormones to increase production. This can lead to animal suffering and contribute to the spread of antibiotic-resistant bacteria. To address these concerns, some companies are now sourcing carnitine from plant-based sources such as beets and corn. This not only reduces the environmental impact of production but also eliminates the ethical concerns associated with animal-based sources. Additionally, some companies are implementing sustainable and ethical sourcing practices for animal-based sources of carnitine, such as sourcing from farms that prioritize animal welfare and environmental sustainability. Overall, the environmental impact and ethical sourcing practices of carnitine depend on the source and production methods used. Consumers can make more informed choices by choosing products that prioritize sustainability and ethical sourcing practices.

Conclusion

In conclusion, carnitine is an important nutrient that plays a crucial role in energy metabolism and fat oxidation. It has been shown to have potential benefits for heart health, exercise performance, and cognitive function. However, excessive intake of carnitine supplements may have negative effects on health, including gastrointestinal distress and an increased risk of cardiovascular disease. Carnitine can be found in animal products such as meat, fish, and dairy, but can also be synthesized by the body. While carnitine is generally considered safe, more research is needed to fully understand its long-term effects. Additionally, the sustainability of carnitine sources, particularly from animal products, is a concern for environmental and ethical reasons.

Leave a Message

Chronic skin issues? Contact us for holistic advice.

powerhouse@mitoskin.org

Copyright 2023 MITOSKIN LLC