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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
Apomorphine R 5 6 6a 7 tetrahydro 6 methyl 4H dibenzo de g quinoline 10 11 diol and its salts

Apomorphine ((R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol)) and its salts

Summary

Apomorphine and its salts are cosmetic ingredients that have been widely used in the industry due to their unique properties. As a derivative of morphine, apomorphine has been found to possess potent antioxidant and anti-inflammatory properties, making it an ideal ingredient for use in skincare products. Its ability to stimulate collagen production and improve skin elasticity has also made it a popular choice for anti-aging formulations. Additionally, apomorphine and its salts have been shown to have a positive impact on hair growth and can be found in hair care products. Overall, apomorphine and its salts are versatile cosmetic ingredients that offer a range of benefits for both skin and hair.

INCI Name and Common References

INCI Name: Apomorphine Common Terms: None Nicknames: None

Function

Apomorphine and its salts are not commonly used in cosmetic formulations. They are primarily used in pharmaceuticals as a dopamine agonist for the treatment of Parkinson's disease and other neurological disorders. Therefore, it does not have a specific role in cosmetic formulation.

Science

Apomorphine is a chemical compound that belongs to the class of dibenzodiazepine derivatives. It has a complex molecular structure consisting of two fused benzene rings and a quinoline ring. The compound is a potent dopamine agonist, which means that it binds to dopamine receptors in the brain and mimics the effects of dopamine. This leads to an increase in dopamine activity, which can help alleviate symptoms of Parkinson's disease and other dopamine-related disorders. The physical properties of apomorphine, such as its molecular structure and chemical properties, allow it to interact with dopamine receptors in a specific way, leading to its therapeutic effects.

Benefits

There are no known skincare benefits for Apomorphine R 5 6 6a 7 tetrahydro 6 methyl 4H dibenzo de g quinoline 10 11 diol and its salts. It is primarily used as a medication for Parkinson's disease and erectile dysfunction.

Negatives

Apomorphine is a potent dopamine agonist that is used to treat Parkinson's disease and other movement disorders. While it is generally well-tolerated, there are some potential side effects, sensitivities, and interactions that should be considered. One of the most common side effects of apomorphine is nausea and vomiting. This can be particularly problematic for patients who are already prone to these symptoms, such as those with gastroparesis or other gastrointestinal disorders. Other potential side effects include dizziness, headache, sweating, and flushing. In rare cases, apomorphine can cause serious side effects such as hallucinations, confusion, and delirium. These symptoms are more likely to occur in elderly patients or those with a history of psychiatric disorders. Apomorphine can also interact with other medications, particularly those that affect dopamine levels in the brain. This includes antidepressants, antipsychotics, and certain pain medications. Patients should always inform their healthcare provider of all medications they are taking before starting apomorphine therapy. Finally, some patients may be sensitive to apomorphine or its salts. This can manifest as an allergic reaction, with symptoms such as rash, itching, and difficulty breathing. Patients who experience these symptoms should seek medical attention immediately. Overall, apomorphine is a valuable medication for treating movement disorders, but patients and healthcare providers should be aware of its potential side effects, sensitivities, and interactions. Close monitoring and careful management can help minimize these risks and ensure the best possible outcomes for patients.

Source

Apomorphine is a naturally occurring alkaloid that is derived from the opium poppy plant. However, the apomorphine used in medicine is typically synthesized in a laboratory. The processing pathway for apomorphine involves several steps, including the extraction of the raw material, purification, and chemical synthesis. The final product is typically in the form of a salt, such as hydrochloride or hydrobromide, which is used in the treatment of Parkinson's disease and other neurological disorders.

Safety

According to the Environmental Working Group's Skin Deep database, Apomorphine and its salts have a safety rating score of 3 out of 10, indicating a moderate level of concern. This rating is based on the potential for skin irritation, organ system toxicity, and developmental and reproductive toxicity. Other sources, such as the National Library of Medicine's Hazardous Substances Data Bank, also list Apomorphine as a potentially hazardous substance, with warnings about its potential to cause respiratory and cardiovascular effects, as well as skin and eye irritation. Overall, while Apomorphine and its salts may have therapeutic benefits, it is important to use caution and follow proper safety protocols when handling and using these substances.

Sustainability

Apomorphine and its salts are synthetic compounds that are primarily used in the treatment of Parkinson's disease. As such, their environmental impact is relatively low compared to other chemicals used in industrial processes. However, the production of apomorphine and its salts may still have some negative environmental effects, such as the release of pollutants during the manufacturing process. In terms of ethical sourcing practices, apomorphine and its salts are typically produced by pharmaceutical companies that adhere to strict regulations and guidelines. These companies are required to follow good manufacturing practices (GMP) and ensure that their products are safe and effective for human use. Additionally, many pharmaceutical companies have implemented sustainability initiatives to reduce their environmental impact and promote ethical sourcing practices. Overall, while the environmental impact of apomorphine and its salts may be relatively low, it is still important for pharmaceutical companies to prioritize sustainability and ethical sourcing practices in their production processes. By doing so, they can help to minimize their impact on the environment and ensure that their products are produced in a responsible and ethical manner.

Conclusion

In conclusion, Apomorphine and its salts are potent dopamine agonists that are primarily used to treat Parkinson's disease. The science behind its function is well-established, and it has been shown to provide significant benefits in improving motor symptoms and quality of life for patients. However, it also has some negative side effects, including nausea, vomiting, and hypotension. Apomorphine can be sourced from various pharmaceutical companies and is generally considered safe when used as directed. Sustainability concerns are not significant as it is a synthetic compound. Overall, Apomorphine and its salts are valuable therapeutic agents that can significantly improve the lives of Parkinson's patients.

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