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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
Acetorphine

Acetorphine

Summary

Acetorphine is a potent opioid analgesic that is commonly used in veterinary medicine. It is a synthetic derivative of thebaine and has a high affinity for mu-opioid receptors. Acetorphine is known for its fast onset of action and short duration of effect, making it an ideal choice for use in surgical procedures. However, due to its high potency and potential for abuse, it is strictly regulated and not approved for use in humans. As a cosmetic ingredient, acetorphine is not commonly used due to its potential for adverse effects and regulatory restrictions.

INCI Name and Common References

INCI name: Acetorphine Common terms: None Nicknames: None

Function

Acetorphine is not a common ingredient in cosmetic formulation. It is a potent opioid analgesic used in veterinary medicine for pain relief in animals. Its use in cosmetic formulation is not recommended due to its potential for abuse and addiction.

Science

Acetorphine is a synthetic opioid that works by binding to specific receptors in the brain and spinal cord. These receptors are known as mu-opioid receptors, and they are responsible for regulating pain perception, mood, and other physiological processes. Acetorphine's chemical structure allows it to bind tightly to these receptors, which leads to a reduction in pain and an increase in feelings of euphoria and relaxation. Additionally, acetorphine has a high affinity for these receptors, meaning that it can bind to them even at low concentrations, making it a potent painkiller. Overall, acetorphine's physical properties allow it to effectively target and modulate the mu-opioid receptors, leading to its therapeutic effects.

Benefits

There are no skincare benefits associated with Acetorphine. It is a potent opioid analgesic used for pain management in medical settings. However, it is not safe or recommended for use in skincare products.

Negatives

Acetorphine is a potent opioid analgesic that is used in veterinary medicine to treat pain in animals. While it is generally safe when used as directed, there are some potential side effects, sensitivities, and interactions that should be considered. One of the most significant risks associated with acetorphine is respiratory depression. This can occur when the drug is used in high doses or in animals with pre-existing respiratory conditions. Signs of respiratory depression include slow or shallow breathing, blue or pale gums, and lethargy. If these symptoms are observed, the animal should be monitored closely and supportive care should be provided as needed. Another potential side effect of acetorphine is sedation. This can be beneficial in some cases, such as when the animal is in pain and needs to rest, but it can also be problematic if the animal needs to be alert and active. In addition, acetorphine can cause gastrointestinal upset, including nausea, vomiting, and diarrhea. Acetorphine can also interact with other drugs, particularly other opioids and sedatives. This can increase the risk of respiratory depression and other side effects. It is important to inform the veterinarian of any other medications the animal is taking before administering acetorphine. Finally, some animals may be sensitive to acetorphine and may experience an allergic reaction. Signs of an allergic reaction include swelling, hives, difficulty breathing, and collapse. If these symptoms are observed, the animal should be treated immediately with supportive care and, if necessary, epinephrine. Overall, acetorphine is a powerful medication that can be very effective in treating pain in animals. However, it is important to use it with caution and to be aware of the potential side effects, sensitivities, and interactions that may occur.

Source

Acetorphine is a synthetic opioid that was first synthesized in the 1960s by a team of researchers at Janssen Pharmaceutica. It is derived from thebaine, which is a natural alkaloid found in opium poppies. The processing pathway for acetorphine involves several steps of chemical synthesis, starting with thebaine as the starting material. Thebaine is first converted into oripavine, which is then further modified to produce the intermediate compound thevinone. Thevinone is then reacted with various reagents to produce the final product, acetorphine. Acetorphine is primarily used as a veterinary anesthetic and analgesic, and is not approved for human use in most countries due to its high potential for abuse and addiction.

Safety

Acetorphine is a potent opioid analgesic that is primarily used in veterinary medicine. As a result, it is not typically rated by consumer-focused safety rating systems such as EWG Skin Deep. However, it is regulated by government agencies such as the FDA and is classified as a Schedule II controlled substance due to its high potential for abuse and dependence. It should only be used under the supervision of a licensed veterinarian and with extreme caution due to its potential for respiratory depression and other serious side effects. Overall, while Acetorphine may be effective for its intended use, it is not considered safe for human use and should only be used in veterinary medicine under strict supervision.

Sustainability

Acetorphine is a synthetic opioid that is primarily used as a veterinary anesthetic. As such, its environmental impact is relatively low as it is not commonly used in large quantities. However, the production of acetorphine and other opioids can have negative environmental impacts due to the chemicals and waste products involved in the manufacturing process. In terms of ethical sourcing practices, there are concerns about the use of opioids in veterinary medicine and the potential for misuse or abuse. Some animal welfare advocates argue that the use of opioids like acetorphine can be cruel and inhumane, particularly if animals are not properly anesthetized or monitored during procedures. There are also concerns about the use of opioids in human medicine and the potential for addiction and overdose. As such, many pharmaceutical companies and healthcare providers are working to develop alternative pain management strategies that are less reliant on opioids. Overall, while acetorphine itself may not have a significant environmental impact, its use raises important ethical questions about animal welfare and the responsible use of opioids in both veterinary and human medicine.

Conclusion

In conclusion, Acetorphine is a potent opioid analgesic that is primarily used in veterinary medicine. Its function is to provide pain relief to animals undergoing surgery or other medical procedures. The science behind Acetorphine is well-established, and it works by binding to opioid receptors in the brain and spinal cord. The benefits of Acetorphine include its fast-acting pain relief and its ability to sedate animals during medical procedures. However, there are also some negatives associated with its use, including the potential for addiction and overdose. Acetorphine is derived from the opium poppy, and it can be sourced from various countries around the world. While it is generally considered safe when used as directed, it can be dangerous if misused or abused. In terms of sustainability, the production of Acetorphine can have negative environmental impacts, and there is a need for responsible sourcing and disposal practices. Overall, Acetorphine is an important tool in veterinary medicine, but its use should be carefully monitored and regulated to ensure the safety of both animals and humans.

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