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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

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Ingredient
7DEHYDROCHOLESTEROL

7-DEHYDROCHOLESTEROL

Summary

7-Dehydrocholesterol is a naturally occurring steroid found in the skin that is converted to vitamin D3 upon exposure to UV light. In cosmetics, it is used as a skin conditioning agent and emollient, helping to improve skin texture and hydration. It also has antioxidant properties, protecting the skin from environmental stressors. 7-Dehydrocholesterol is a safe and effective ingredient that can be found in a variety of skincare and personal care products.

INCI Name and Common References

INCI Name: 7-Dehydrocholesterol Common Terms: Provitamin D3 Nicknames: None

Function

7-Dehydrocholesterol is a precursor to vitamin D3 and is used in cosmetic formulations as a skin conditioning agent. It helps to improve the texture and appearance of the skin by promoting cell growth and regeneration. It also has antioxidant properties that protect the skin from damage caused by free radicals. Additionally, it can help to enhance the penetration of other active ingredients in the formulation, making them more effective.

Science

7-dehydrocholesterol is a precursor molecule for the synthesis of vitamin D3 in the skin. When exposed to UVB radiation from sunlight, 7-dehydrocholesterol undergoes a photochemical reaction that converts it into pre-vitamin D3. This pre-vitamin D3 is then converted into vitamin D3 through a thermal process. Vitamin D3 is essential for calcium absorption and bone health, as well as immune system function and regulation of cell growth and differentiation. Therefore, 7-dehydrocholesterol plays a crucial role in the body's ability to produce vitamin D3 and maintain overall health.

Benefits

As an ingredient in skincare products, 7-dehydrocholesterol is known to have several benefits. It is a precursor to vitamin D, which helps to improve skin health and reduce inflammation. It also helps to protect the skin from UV damage and can improve the appearance of fine lines and wrinkles. Additionally, 7-dehydrocholesterol can help to improve skin hydration and elasticity, leaving the skin looking and feeling smoother and more youthful.

Negatives

7-dehydrocholesterol is a precursor to vitamin D3 and is found in the skin of humans and animals. While it is generally considered safe, there are some potential side effects, sensitivities, and interactions to be aware of. Side effects: - High doses of vitamin D3, which is produced from 7-dehydrocholesterol, can lead to hypercalcemia (high levels of calcium in the blood), which can cause kidney damage, heart problems, and other health issues. - Some people may experience gastrointestinal symptoms such as nausea, vomiting, and constipation when taking vitamin D supplements. Sensitivities: - Some people may be allergic to vitamin D supplements, which can cause symptoms such as hives, itching, and difficulty breathing. - People with certain medical conditions, such as hyperparathyroidism, sarcoidosis, and lymphoma, may be more sensitive to vitamin D supplements and should consult with a healthcare provider before taking them. Interactions: - Vitamin D supplements can interact with certain medications, including corticosteroids, antacids, and some cholesterol-lowering drugs, which can affect their effectiveness or increase the risk of side effects. - Vitamin D supplements can also interact with other supplements, such as calcium and magnesium, which can affect their absorption and metabolism in the body. Overall, while 7-dehydrocholesterol is an important precursor to vitamin D3, it is important to be aware of potential side effects, sensitivities, and interactions when taking vitamin D supplements. It is always recommended to consult with a healthcare provider before starting any new supplement regimen.

Source

7-Dehydrocholesterol is a natural ingredient that originates from animal sources, particularly sheep's wool. It is a precursor to vitamin D3 and is converted to vitamin D3 through exposure to UV light. The processing pathway involves extraction of the wool grease, purification of the 7-dehydrocholesterol, and then exposure to UV light to convert it to vitamin D3.

Safety

The safety rating score for 7-Dehydrocholesterol varies depending on the rating system used. According to the Environmental Working Group's Skin Deep database, 7-Dehydrocholesterol has a low hazard rating of 1 out of 10, indicating that it is considered safe for use in cosmetics and personal care products. However, other sources may have different safety ratings for this ingredient. It is always important to research and consider multiple sources when evaluating the safety of any ingredient.

Sustainability

7-Dehydrocholesterol is a naturally occurring compound found in the skin of animals and humans. It is a precursor to vitamin D3, which is essential for maintaining healthy bones and teeth. However, the environmental impact of 7-dehydrocholesterol is not significant as it is a naturally occurring compound and does not require any specific cultivation or extraction process. In terms of ethical sourcing practices, 7-dehydrocholesterol is typically sourced from animal by-products, such as sheep wool grease or lanolin. While the use of animal by-products is not inherently unethical, there are concerns about the treatment of animals in the wool industry. Some companies have implemented ethical sourcing practices, such as ensuring that the wool is sourced from farms that prioritize animal welfare and do not use mulesing, a controversial practice that involves removing strips of skin from the sheep's hindquarters to prevent flystrike. Overall, while the environmental impact of 7-dehydrocholesterol is minimal, it is important for companies to prioritize ethical sourcing practices when obtaining this ingredient from animal by-products. By doing so, they can ensure that the animals are treated humanely and that their products are produced in a sustainable and responsible manner.

Conclusion

In conclusion, 7-dehydrocholesterol is a crucial ingredient in the human body that plays a vital role in the production of vitamin D. It is synthesized in the skin and converted to vitamin D through exposure to sunlight. While it has numerous benefits, including maintaining healthy bones and teeth, it can also have negative effects if consumed in excess. It is found in animal products such as eggs, liver, and fatty fish. The safety of 7-dehydrocholesterol is well established, and it is considered safe for consumption in moderate amounts. However, sustainability is a concern as overfishing and unsustainable farming practices can lead to a decline in the availability of sources. Overall, 7-dehydrocholesterol is an essential ingredient that should be consumed in moderation for optimal health benefits.

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