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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
4tetrahydro2Hpyran2yloxyphenolDeoxyarbutinTetrahydropyranyloxyPhenol

4-[(tetrahydro-2H-pyran-2-yl)oxy]phenol (Deoxyarbutin, Tetrahydropyranyloxy Phenol)

Summary

Deoxyarbutin, also known as Tetrahydropyranyloxy Phenol, is a cosmetic ingredient that is derived from hydroquinone. It is a safe and effective skin lightening agent that inhibits the production of melanin, resulting in a brighter and more even skin tone. Deoxyarbutin is also known for its antioxidant properties, which help to protect the skin from environmental stressors and premature aging. Its unique chemical structure allows for better stability and penetration into the skin, making it a popular choice in many skincare formulations.

INCI Name and Common References

4-[(tetrahydro-2H-pyran-2-yl)oxy]phenol (INCI name), also known as Deoxyarbutin or Tetrahydropyranyloxy Phenol.

Function

Deoxyarbutin, also known as Tetrahydropyranyloxy Phenol, is a skin-lightening agent that is commonly used in cosmetic formulations. It works by inhibiting the production of melanin, which is responsible for skin pigmentation. This ingredient is often used in products designed to treat hyperpigmentation, age spots, and other skin discolorations. Additionally, Deoxyarbutin has antioxidant properties that can help protect the skin from damage caused by free radicals. Overall, this ingredient plays an important role in cosmetic formulation by helping to improve the appearance and health of the skin.

Science

Deoxyarbutin works by inhibiting the activity of tyrosinase, an enzyme involved in the production of melanin. Its physical properties, specifically its chemical structure, allow it to penetrate the skin more easily than traditional arbutin. The tetrahydropyranyl group in deoxyarbutin increases its solubility in water and enhances its stability, making it a more effective skin lightening agent. Additionally, the phenolic group in deoxyarbutin acts as an antioxidant, protecting the skin from damage caused by free radicals.

Benefits

1. Brightening: Deoxyarbutin is known to inhibit the production of melanin, which can help to reduce the appearance of dark spots and hyperpigmentation. 2. Anti-aging: This ingredient has antioxidant properties that can help to protect the skin from damage caused by free radicals, which can contribute to premature aging. 3. Moisturizing: Deoxyarbutin has hydrating properties that can help to improve the skin's moisture levels, leaving it feeling soft and supple. 4. Even skin tone: By reducing the appearance of dark spots and hyperpigmentation, Deoxyarbutin can help to even out the skin tone, giving it a more uniform appearance. 5. Gentle: Unlike some other skin brightening ingredients, Deoxyarbutin is considered to be gentle and non-irritating, making it suitable for use on sensitive skin.

Negatives

Deoxyarbutin, also known as Tetrahydropyranyloxy Phenol, is a skin-lightening agent that is commonly used in cosmetic products. While it is generally considered safe for use, there are some potential side effects, sensitivities, and interactions that should be taken into consideration. One of the main concerns with Deoxyarbutin is that it may cause skin irritation or allergic reactions in some individuals. This can manifest as redness, itching, or swelling of the skin. If you experience any of these symptoms after using a product containing Deoxyarbutin, you should discontinue use immediately and consult with a healthcare professional. Another potential issue with Deoxyarbutin is that it may interact with other ingredients in cosmetic products. For example, it may react with certain preservatives or fragrances, leading to decreased efficacy or increased risk of irritation. It is important to carefully read the labels of any products containing Deoxyarbutin and to avoid using them in combination with other products that may contain potentially irritating or reactive ingredients. Finally, it is worth noting that Deoxyarbutin may not be suitable for all skin types. While it is generally considered safe for use on most skin types, individuals with sensitive or reactive skin may be more prone to experiencing side effects or allergic reactions. If you have any concerns about using products containing Deoxyarbutin, it is always best to consult with a healthcare professional or dermatologist before use.

Source

Deoxyarbutin is a synthetic ingredient that is derived from hydroquinone, a natural compound found in certain plants. The processing pathway involves the conversion of hydroquinone into arbutin, which is then further modified to produce deoxyarbutin. This process involves the use of various chemical reagents and solvents, and the final product is purified to remove any impurities. Deoxyarbutin is commonly used in skincare products as a skin lightening agent due to its ability to inhibit the production of melanin.

Safety

According to the Environmental Working Group's Skin Deep database, Deoxyarbutin has a safety rating of 1, which is considered to be a low hazard. This rating is based on the ingredient's low potential for skin irritation and toxicity. Other sources also indicate that Deoxyarbutin is generally safe for use in cosmetics and personal care products. However, as with any ingredient, it is important to use Deoxyarbutin in accordance with recommended guidelines and to discontinue use if any adverse reactions occur.

Sustainability

Deoxyarbutin, also known as Tetrahydropyranyloxy Phenol, is a skin-lightening ingredient commonly used in cosmetic products. While there is limited information available on its environmental impact, it is important to consider the ethical sourcing practices of this ingredient. Deoxyarbutin is derived from hydroquinone, a controversial skin-lightening ingredient that has been banned in several countries due to its potential health risks. However, Deoxyarbutin is considered a safer alternative to hydroquinone, as it does not have the same potential for toxicity. In terms of ethical sourcing practices, it is important to ensure that the hydroquinone used to produce Deoxyarbutin is obtained from sustainable and ethical sources. This means that the production of hydroquinone should not contribute to deforestation, habitat destruction, or human rights abuses. Additionally, it is important to consider the potential impact of Deoxyarbutin on the environment once it is used in cosmetic products. While there is limited information available on this topic, it is possible that Deoxyarbutin could contribute to water pollution or other environmental issues if it is not properly disposed of. Overall, while there is limited information available on the environmental impact of Deoxyarbutin, it is important to consider the ethical sourcing practices of this ingredient and to ensure that it is used in a responsible and sustainable manner.

Conclusion

In conclusion, Deoxyarbutin is a skin-lightening ingredient that functions by inhibiting the production of melanin. Its scientific studies have shown that it is more effective and safer than its predecessor, hydroquinone. The benefits of Deoxyarbutin include its ability to reduce hyperpigmentation, age spots, and melasma. However, its negative side effects include skin irritation and sensitivity. Deoxyarbutin can be sourced from various plants, including bearberry, blueberry, and cranberry. It is considered safe for use in cosmetics and skincare products, but its sustainability is still under investigation. Overall, Deoxyarbutin is a promising ingredient in the skincare industry, but further research is needed to determine its long-term safety and sustainability.

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