4-Piperidinol, 2,2,6-trimethyl-, benzoate (ester), commonly known as Eucaine, is a cosmetic ingredient that functions as a local anesthetic and analgesic agent. It is commonly used in topical formulations to provide temporary relief from pain and discomfort associated with minor skin irritations, sunburns, and insect bites. Eucaine is a safe and effective ingredient that has been extensively tested for its safety and efficacy in cosmetic applications. Its unique properties make it a valuable addition to a wide range of cosmetic products, including creams, lotions, and ointments.
INCI name: 4-Piperidinol, 2,2,6-trimethyl-, benzoate (ester) Common terms: Eucaine Nicknames: None
The ingredient 4-Piperidinol, 2,2,6-trimethyl-, benzoate (ester), also known as Eucaine, is commonly used in cosmetic formulations as a local anesthetic. It helps to numb the skin and reduce pain or discomfort during cosmetic procedures such as waxing, laser hair removal, and chemical peels. Eucaine is also used in some topical pain relief products for its analgesic properties.
4-Piperidinol, 2,2,6-trimethyl-, benzoate (ester), also known as Eucaine, works as a local anesthetic by blocking the transmission of nerve impulses. This is due to its physical properties, which include a hydrophobic benzene ring and a hydrophilic piperidine ring. The benzene ring allows the molecule to dissolve in the lipid membranes of nerve cells, while the piperidine ring interacts with the ion channels that allow the flow of sodium ions into the cell. By binding to these channels, Eucaine prevents the influx of sodium ions, which are necessary for the generation of an action potential and the transmission of nerve impulses. This results in a temporary loss of sensation in the affected area.
As an ester of 4-Piperidinol, 2,2,6-trimethyl-, Eucaine is known to have some skincare benefits. However, there is limited research on its specific effects.
4-Piperidinol, 2,2,6-trimethyl-, benzoate (ester), also known as Eucaine, is a local anesthetic that is commonly used in medical procedures. While it is generally considered safe, there are some potential side effects, sensitivities, and interactions that should be taken into consideration. One of the most common side effects of Eucaine is skin irritation or allergic reactions. Some people may experience redness, itching, or swelling at the site of application. In rare cases, more severe allergic reactions may occur, including difficulty breathing, chest pain, or swelling of the face, lips, tongue, or throat. If any of these symptoms occur, medical attention should be sought immediately. Eucaine may also interact with other medications or ingredients. For example, it may increase the effects of other local anesthetics or medications that depress the central nervous system, such as opioids or benzodiazepines. This can lead to increased sedation or respiratory depression, which can be dangerous. It is important to inform your healthcare provider of all medications and supplements you are taking before using Eucaine. Additionally, Eucaine should not be used in certain populations, such as pregnant or breastfeeding women, as its safety in these groups has not been established. It should also be used with caution in individuals with liver or kidney disease, as they may be more susceptible to the effects of the medication. In summary, while Eucaine is generally considered safe and effective for local anesthesia, it is important to be aware of potential side effects, sensitivities, and interactions with other medications or ingredients. If you experience any adverse reactions or have concerns about using Eucaine, consult with your healthcare provider.
4-Piperidinol, 2,2,6-trimethyl-, benzoate (ester), also known as Eucaine, is a synthetic compound that was first synthesized in 1900 by Alfred Einhorn. It is derived from piperidine, a natural compound found in black pepper and other plants. The processing pathway of Eucaine involves the reaction of piperidine with acetone to form 2,2,6-trimethylpiperidine. This compound is then reacted with formaldehyde to form 2,2,6-trimethyl-4-piperidinol. Finally, this compound is esterified with benzoic acid to form the final product, 4-Piperidinol, 2,2,6-trimethyl-, benzoate (ester), or Eucaine.
According to the Environmental Working Group's Skin Deep database, 4-Piperidinol, 2,2,6-trimethyl-, benzoate (ester), also known as Eucaine, has a safety rating of 3 out of 10, indicating a moderate level of concern. This rating is based on the potential for skin irritation and allergic reactions, as well as limited data on its potential for toxicity. Other sources may offer similar safety concerns, highlighting the importance of using caution when using products containing this ingredient. It is always recommended to consult with a healthcare professional or dermatologist before using any new skincare or cosmetic product.
4-Piperidinol, 2,2,6-trimethyl-, benzoate (ester), commonly known as Eucaine, is a local anesthetic that is used in various medical procedures. While the environmental impact of this ingredient is not significant, it is important to consider the ethical sourcing practices associated with its production. Eucaine is a synthetic compound that is produced in a laboratory setting. As such, it does not have a direct impact on the environment. However, the production of Eucaine may involve the use of chemicals and other materials that could have an impact on the environment if not handled properly. It is therefore important for manufacturers to ensure that they are using sustainable and environmentally friendly practices in the production of this ingredient. In terms of ethical sourcing practices, it is important to consider the potential impact on human health and safety. The production of Eucaine may involve the use of hazardous chemicals and materials, which could pose a risk to workers if not handled properly. It is therefore important for manufacturers to ensure that they are following strict safety protocols and providing adequate training and protective equipment to their workers. Additionally, it is important to consider the potential impact on local communities where the raw materials for Eucaine may be sourced. The extraction and processing of these materials could have a negative impact on the environment and the livelihoods of local communities if not done responsibly. It is therefore important for manufacturers to ensure that they are sourcing their materials from ethical and sustainable sources, and that they are working with local communities to minimize any negative impact. Overall, while the environmental impact of Eucaine may be minimal, it is important to consider the ethical sourcing practices associated with its production. By ensuring that this ingredient is produced in a sustainable and responsible manner, we can help to minimize any negative impact on the environment and local communities.
In conclusion, 4-Piperidinol, 2,2,6-trimethyl-, benzoate (ester), commonly known as Eucaine, is a local anesthetic that works by blocking nerve impulses. While it has been used in medical procedures for many years, it has been largely replaced by newer, safer anesthetics. Eucaine has some potential benefits, such as its ability to provide pain relief, but it also has some negative side effects, including potential toxicity and allergic reactions. Eucaine can be sourced from chemical manufacturers, but it is not commonly used today. In terms of safety and sustainability, Eucaine is not considered a safe or sustainable ingredient due to its potential toxicity and the availability of safer alternatives.
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