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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
4NITROOPHENYLENEDIAMINE

4-NITRO-O-PHENYLENEDIAMINE

Summary

4-Nitro-o-phenylenediamine is a cosmetic ingredient commonly used as a hair dye. It is a yellow crystalline powder that is soluble in water and ethanol. This ingredient is known for its ability to provide long-lasting color to hair, and is often used in combination with other dyes to achieve a desired shade. However, it is important to note that 4-nitro-o-phenylenediamine has been associated with allergic reactions in some individuals, and should be used with caution. Overall, this ingredient is a popular choice for hair dye formulations due to its effectiveness and versatility.

INCI Name and Common References

INCI Name: 4-Nitro-o-phenylenediamine Common Terms: Nitrophenylenediamine, 4-Nitro-1,2-phenylenediamine Nicknames: NPD, 4-Nitro-PPD

Function

4-NITRO-O-PHENYLENEDIAMINE is a hair dye ingredient that is used to provide a permanent color to the hair. It works by penetrating the hair shaft and reacting with the natural melanin in the hair to produce a new color. However, it can also cause skin irritation and allergic reactions in some individuals, so it is important to use it in a safe and controlled manner.

Science

4-Nitro-o-phenylenediamine is a chemical compound with a nitro group (-NO2) and two amino groups (-NH2) attached to a phenyl ring. Its physical properties include a melting point of 146-148°C and a solubility in water of 0.1 g/L at 20°C. In hair dye products, 4-nitro-o-phenylenediamine acts as a colorant by reacting with the hair protein keratin. The amino groups on the compound can form covalent bonds with the amino acids in keratin, resulting in a stable dye molecule that is resistant to washing out. The nitro group on the compound also contributes to its color by absorbing light in the visible spectrum. However, 4-nitro-o-phenylenediamine has been found to have potential health risks, including skin irritation and sensitization, and has been banned or restricted in some countries.

Benefits

Unfortunately, 4-NITRO-O-PHENYLENEDIAMINE is not a skincare ingredient that is commonly used or recommended due to its potential toxicity and harmful effects on the skin. It is important to always research and consult with a dermatologist before using any new skincare ingredient.

Negatives

4-NITRO-O-PHENYLENEDIAMINE is a chemical compound that is commonly used in hair dyes and other cosmetic products. While it is generally considered safe for use in these products, there are some potential side effects, sensitivities, and interactions that should be considered. One of the main concerns with 4-NITRO-O-PHENYLENEDIAMINE is its potential to cause allergic reactions. Some people may be sensitive to this ingredient and experience symptoms such as itching, redness, and swelling of the skin. In severe cases, an allergic reaction can lead to anaphylaxis, a life-threatening condition that requires immediate medical attention. Another potential side effect of 4-NITRO-O-PHENYLENEDIAMINE is skin irritation. This can occur even in people who are not allergic to the ingredient, and may manifest as redness, itching, or a burning sensation on the skin. In some cases, prolonged exposure to this ingredient can lead to more serious skin conditions such as dermatitis or eczema. Finally, there is some concern that 4-NITRO-O-PHENYLENEDIAMINE may interact with other ingredients in cosmetic products. For example, it may react with hydrogen peroxide, a common ingredient in hair dyes, to produce toxic byproducts. This can be particularly dangerous if the product is not used according to the manufacturer's instructions or if it is used on damaged or sensitive skin. Overall, while 4-NITRO-O-PHENYLENEDIAMINE is generally considered safe for use in cosmetic products, it is important to be aware of the potential side effects, sensitivities, and interactions that may occur. If you experience any adverse reactions after using a product containing this ingredient, it is important to seek medical attention right away.

Source

4-NITRO-O-PHENYLENEDIAMINE is a synthetic ingredient that is derived from coal tar. It is commonly used as a hair dye and is also found in some cosmetic products. The processing pathway for this ingredient involves the nitration of o-phenylenediamine with nitric acid to produce 4-nitro-o-phenylenediamine.

Safety

The safety rating score for 4-NITRO-O-PHENYLENEDIAMINE is generally considered to be low based on various rating systems such as EWG Skin Deep. This chemical is classified as a skin irritant and sensitizer, which means it can cause allergic reactions and skin irritation. It is also classified as a possible human carcinogen by the International Agency for Research on Cancer (IARC). Therefore, it is recommended to avoid products containing this ingredient or use them with caution. It is important to note that the safety rating score may vary depending on the concentration and usage of the chemical in a product.

Sustainability

4-NITRO-O-PHENYLENEDIAMINE is a chemical compound that is commonly used in the production of hair dyes and other cosmetic products. Unfortunately, this ingredient has a significant environmental impact and raises concerns about ethical sourcing practices. Firstly, the production of 4-NITRO-O-PHENYLENEDIAMINE involves the use of various chemicals and processes that can have harmful effects on the environment. For example, the synthesis of this compound requires the use of nitric acid, which is a highly corrosive and toxic substance that can cause serious environmental damage if not handled properly. Additionally, the disposal of waste products from the production process can also contribute to pollution and other environmental problems. Furthermore, there are concerns about the ethical sourcing of 4-NITRO-O-PHENYLENEDIAMINE. This ingredient is often derived from coal tar, which is a byproduct of the coal industry. Coal mining is known to have significant environmental and social impacts, including deforestation, water pollution, and displacement of local communities. Additionally, there are concerns about the safety and working conditions of coal miners, particularly in developing countries where labor laws may be less stringent. Overall, the use of 4-NITRO-O-PHENYLENEDIAMINE raises important questions about the environmental impact and ethical sourcing practices of the cosmetic industry. As consumers, it is important to be aware of these issues and to support companies that prioritize sustainability and ethical sourcing in their products.

Conclusion

In conclusion, 4-nitro-o-phenylenediamine is a chemical ingredient commonly used in hair dyes and other cosmetic products. While it is effective in coloring hair, it has been linked to negative health effects such as skin irritation and allergic reactions. It is derived from coal tar and can also be found in some natural sources. The safety of this ingredient is a concern, and it is important to use it in moderation and with caution. Additionally, the sustainability of its production and use is questionable, as it is a non-renewable resource. Overall, it is important to weigh the benefits and negatives of using 4-nitro-o-phenylenediamine and consider alternative, safer options.

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