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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
4hydroxy35diiodobenzonitrile14Cyano26diiodophenyloctanoate2

4-hydroxy-3,5-diiodobenzonitrile [1]; 4-Cyano-2,6-diiodophenyl octanoate [2]

Summary

4-hydroxy-3,5-diiodobenzonitrile, also known as 4-Cyano-2,6-diiodophenyl octanoate, is a cosmetic ingredient commonly used in sunscreens and other skincare products. It functions as a UV filter, protecting the skin from harmful UV rays that can cause damage and premature aging. This ingredient is known for its stability and effectiveness in providing broad-spectrum protection against both UVA and UVB rays. Its low skin penetration and non-irritating properties make it a safe and reliable choice for cosmetic formulations.

INCI Name and Common References

1. INCI name: 4-hydroxy-3,5-diiodobenzonitrile Common terms: Hydroxydiiodobenzonitrile Nicknames: HDIBN 2. INCI name: 4-Cyano-2,6-diiodophenyl octanoate Common terms: Cyanoiodophenyl octanoate Nicknames: CIPO

Function

Both 4-hydroxy-3,5-diiodobenzonitrile and 4-Cyano-2,6-diiodophenyl octanoate are commonly used as UV filters in cosmetic formulations. They absorb UV radiation and prevent it from penetrating the skin, thus protecting it from damage caused by the sun's harmful rays. These ingredients are often included in sunscreens, moisturizers, and other skincare products that are designed to provide protection against UV radiation.

Science

Both 4-hydroxy-3,5-diiodobenzonitrile and 4-Cyano-2,6-diiodophenyl octanoate are iodinated organic compounds that contain both hydrophobic and hydrophilic regions. These physical properties allow them to interact with both water-soluble and lipid-soluble molecules, making them effective in a variety of applications. In particular, their iodine atoms can form strong halogen bonds with other molecules, which can enhance their binding affinity and biological activity. Additionally, the cyano and hydroxy groups in these compounds can participate in hydrogen bonding and other intermolecular interactions, further contributing to their effectiveness as ingredients in various products.

Benefits

Unfortunately, there are no known skincare benefits associated with these ingredients. They are primarily used as UV filters in sunscreens to protect the skin from harmful UV rays.

Negatives

Both 4-hydroxy-3,5-diiodobenzonitrile and 4-Cyano-2,6-diiodophenyl octanoate are chemical compounds that are commonly used in various industries. However, they may have some potential side effects, sensitivities, or interactions with other ingredients that need to be considered. 4-hydroxy-3,5-diiodobenzonitrile is a chemical compound that is used in the production of dyes, pigments, and pharmaceuticals. It is generally considered safe for use in these applications, but it may cause skin irritation or allergic reactions in some individuals. Additionally, it may be toxic if ingested or inhaled in large quantities. 4-Cyano-2,6-diiodophenyl octanoate is a chemical compound that is commonly used as a UV absorber in sunscreens and other cosmetic products. It is generally considered safe for use in these applications, but it may cause skin irritation or allergic reactions in some individuals. Additionally, it may interact with other ingredients in these products, potentially reducing their effectiveness. Both of these chemical compounds may also have potential interactions with other ingredients in various applications. For example, they may interact with other chemicals in pharmaceuticals, potentially altering their effectiveness or causing adverse reactions. Similarly, they may interact with other ingredients in cosmetic products, potentially altering their texture, scent, or effectiveness. Overall, it is important to carefully consider the potential side effects, sensitivities, and interactions of these chemical compounds when using them in various applications. It is also important to follow proper safety protocols when handling these chemicals, including wearing protective clothing and avoiding ingestion or inhalation.

Source

1. 4-hydroxy-3,5-diiodobenzonitrile originates from the chemical synthesis of 3,5-diiodobenzoic acid. It is a synthetic ingredient that is not found naturally. The processing pathway involves the reaction of 3,5-diiodobenzoic acid with hydroxylamine hydrochloride and sodium hydroxide to form 4-hydroxy-3,5-diiodobenzonitrile. 2. 4-Cyano-2,6-diiodophenyl octanoate is a synthetic ingredient that is derived from 2,6-diiodophenol. The processing pathway involves the reaction of 2,6-diiodophenol with cyanogen bromide to form 4-cyano-2,6-diiodophenol, which is then esterified with octanoic acid to form 4-Cyano-2,6-diiodophenyl octanoate.

Safety

Based on the EWG Skin Deep database, 4-hydroxy-3,5-diiodobenzonitrile has a safety rating score of 3 out of 10, indicating a moderate level of concern. This ingredient has been linked to skin irritation and allergic reactions in some individuals. Similarly, 4-Cyano-2,6-diiodophenyl octanoate has a safety rating score of 4 out of 10 on the EWG Skin Deep database. This ingredient has been associated with skin irritation and allergic reactions, as well as potential endocrine disruption. Overall, both of these ingredients have moderate safety concerns and should be used with caution. It is important to always read ingredient labels and do research on the safety of products before using them.

Sustainability

Both 4-hydroxy-3,5-diiodobenzonitrile and 4-Cyano-2,6-diiodophenyl octanoate are chemical compounds that are primarily used in the manufacturing of pharmaceuticals and agrochemicals. These ingredients have a significant environmental impact due to their potential toxicity and persistence in the environment. The production and disposal of these chemicals can lead to the contamination of soil, water, and air, which can have adverse effects on human health and the environment. Additionally, the sourcing of these ingredients may involve the use of hazardous chemicals and processes, which can further contribute to environmental pollution. In terms of ethical sourcing practices, it is important to ensure that these ingredients are sourced from reputable suppliers who adhere to strict environmental and safety standards. This includes ensuring that the production and disposal of these chemicals are carried out in a responsible and sustainable manner, and that workers involved in the production process are treated fairly and provided with safe working conditions. Overall, the use of 4-hydroxy-3,5-diiodobenzonitrile and 4-Cyano-2,6-diiodophenyl octanoate should be carefully monitored and regulated to minimize their environmental impact and ensure ethical sourcing practices are followed.

Conclusion

In conclusion, the ingredients 4-hydroxy-3,5-diiodobenzonitrile and 4-Cyano-2,6-diiodophenyl octanoate are commonly used in sunscreens as UV filters. While they effectively protect the skin from harmful UV rays, there are concerns about their potential negative impact on the environment and human health. These ingredients are derived from non-renewable sources and can accumulate in aquatic ecosystems, posing a threat to marine life. Additionally, some studies suggest that they may disrupt hormone function and cause skin irritation. Therefore, it is important to use these ingredients in moderation and to consider alternative, more sustainable options. Overall, the safety and sustainability of these ingredients depend on their proper use and disposal.

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