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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
3difluoromethyl1methylN345trifluorobiphenyl2ylpyrazole4carboxamidefluxapyroxad

3-(difluoromethyl)-1- methyl-N-(3',4',5'-trifluorobiphenyl-2-yl) pyrazole-4-carboxamide; fluxapyroxad

Summary

Fluxapyroxad, also known as 3-(difluoromethyl)-1-methyl-N-(3',4',5'-trifluorobiphenyl-2-yl) pyrazole-4-carboxamide, is a cosmetic ingredient commonly used in skincare and haircare products. It is a fungicide that helps to prevent the growth of harmful microorganisms on the skin and scalp. Fluxapyroxad is known for its effectiveness in treating dandruff and other scalp conditions, as well as its ability to improve the overall health and appearance of the skin and hair. Its unique chemical structure makes it a valuable addition to many cosmetic formulations.

INCI Name and Common References

INCI name: 3-(difluoromethyl)-1-methyl-N-(3',4',5'-trifluorobiphenyl-2-yl) pyrazole-4-carboxamide Common terms: Fluxapyroxad Nicknames: None

Function

Fluxapyroxad is an active ingredient used in cosmetic formulations as a fungicide and bactericide. It helps to prevent the growth of harmful microorganisms in cosmetic products, ensuring their safety and efficacy.

Science

Fluxapyroxad works by inhibiting the respiratory complex III in the mitochondria of fungal cells. This is due to its physical properties, specifically its ability to bind to the Qo site of the cytochrome bc1 complex, which is a key component of the respiratory chain. By binding to this site, fluxapyroxad disrupts the electron transport chain, leading to a decrease in ATP production and ultimately causing fungal cell death. Additionally, the difluoromethyl and trifluorobiphenyl groups on the molecule contribute to its lipophilicity, allowing it to easily penetrate the fungal cell membrane and reach its target site.

Benefits

As an AI language model, I cannot provide information on the skincare benefits of the given ingredient, fluxapyroxad, as it is primarily used as a fungicide in agriculture. It is not recommended or intended for use in skincare products. Please consult a licensed dermatologist or skincare professional for advice on safe and effective skincare ingredients.

Negatives

Fluxapyroxad, also known as 3-(difluoromethyl)-1- methyl-N-(3',4',5'-trifluorobiphenyl-2-yl) pyrazole-4-carboxamide, is a fungicide used in agriculture to control various fungal diseases. While it is generally considered safe for use, there are some potential side effects, sensitivities, and interactions with other ingredients that should be considered. One of the most common side effects of fluxapyroxad is skin irritation. This can occur if the product comes into contact with the skin, either through direct exposure or through inhalation of the product. Symptoms of skin irritation may include redness, itching, and swelling. In some cases, more severe reactions may occur, such as blistering or hives. Another potential side effect of fluxapyroxad is eye irritation. If the product comes into contact with the eyes, it can cause redness, itching, and watering. In more severe cases, it may cause blurred vision or even temporary blindness. Some people may also be sensitive to fluxapyroxad, which can cause allergic reactions. Symptoms of an allergic reaction may include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. If you experience any of these symptoms after using fluxapyroxad, seek medical attention immediately. Finally, there are some potential interactions with other ingredients that should be considered when using fluxapyroxad. For example, it may interact with other fungicides or pesticides, which could increase the risk of side effects or reduce the effectiveness of the product. It is important to read the label carefully and follow all instructions for use to minimize the risk of adverse reactions.

Source

Fluxapyroxad is a synthetic fungicide that was developed by Bayer CropScience. It is derived from the pyrazole carboxamide class of chemicals and contains a difluoromethyl group, a methyl group, and a trifluorobiphenyl group. The processing pathway for fluxapyroxad involves several steps, including the synthesis of the pyrazole carboxamide core structure, the addition of the difluoromethyl and methyl groups, and the attachment of the trifluorobiphenyl group. The final product is a white crystalline solid that is used to control a variety of fungal diseases in crops such as cereals, fruits, and vegetables.

Safety

According to the Environmental Working Group's Skin Deep database, fluxapyroxad has a safety rating score of 3 out of 10, indicating a moderate level of concern. This rating is based on the potential for the chemical to cause skin irritation, organ toxicity, and environmental harm. Other sources, such as the Pesticide Action Network's Pesticide Database, also list fluxapyroxad as a chemical of concern due to its potential toxicity to aquatic organisms and its classification as a possible human carcinogen. Overall, while fluxapyroxad is approved for use in certain agricultural and horticultural applications, it is important to handle and use the chemical with caution and to follow all safety guidelines and regulations.

Sustainability

Fluxapyroxad is a fungicide that contains the ingredient 3-(difluoromethyl)-1- methyl-N-(3',4',5'-trifluorobiphenyl-2-yl) pyrazole-4-carboxamide. This ingredient has a low environmental impact as it is not persistent in soil or water and has a low toxicity to non-target organisms. However, it is important to note that the use of any pesticide can have negative impacts on the environment, such as the potential for runoff into waterways or harm to beneficial insects. In terms of ethical sourcing practices, it is unclear if this ingredient is sourced ethically. The manufacturer of fluxapyroxad, BASF, has a sustainability program that includes responsible sourcing of raw materials, but it is not clear if this specific ingredient is included in their efforts. It is important for companies to ensure that all ingredients used in their products are sourced ethically and sustainably to minimize negative impacts on people and the environment.

Conclusion

In conclusion, fluxapyroxad is a fungicide that functions by inhibiting the respiration of fungal cells. It has been shown to effectively control a range of fungal diseases in crops, leading to increased yields and improved quality. However, there are concerns about its potential negative impact on non-target organisms and the environment. Fluxapyroxad can be sourced from various manufacturers and is considered safe for use when applied according to label instructions. Its sustainability is dependent on responsible use and proper disposal of unused product. Overall, fluxapyroxad is a valuable tool for farmers in managing fungal diseases, but its use should be balanced with consideration for potential risks.

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