2-Nitro-4-cresol, also known as Phenol, 4-methyl-2-nitro-, is a cosmetic ingredient commonly used as a preservative in personal care products. It is effective against a wide range of microorganisms and helps to extend the shelf life of cosmetic formulations. However, it is important to use this ingredient in accordance with regulatory guidelines to ensure its safe use in cosmetic products.
INCI Name: 2-Nitro-4-cresol Common Terms: Nitro Cresol, 4-Cresol Nitro Nicknames: NC, 4CN INCI Name: Phenol, 4-methyl-2-nitro- Common Terms: 4-Methyl-2-nitrophenol, P-Methyl-2-nitrophenol Nicknames: PMNP, 4M2NP
2-Nitro-4-cresol or Phenol, 4-methyl-2-nitro- is an antimicrobial agent that is commonly used in cosmetic formulations to prevent the growth of bacteria, fungi, and other microorganisms. It is particularly effective against gram-positive bacteria and is often used in products such as shampoos, conditioners, and lotions. Additionally, it can also act as a preservative, helping to extend the shelf life of cosmetic products. However, it is important to note that this ingredient can be irritating to the skin and eyes, and should be used in concentrations that are safe for human use.
2-Nitro-4-cresol works by inhibiting the growth of microorganisms due to its physical properties. It is a yellow crystalline solid with a melting point of 107-109°C and a boiling point of 315°C. It is slightly soluble in water but highly soluble in organic solvents such as ethanol and acetone. The nitro group (-NO2) in the molecule is responsible for its antimicrobial activity as it can disrupt the cell membrane of microorganisms and inhibit their growth. The methyl group (-CH3) and the hydroxyl group (-OH) in the molecule also contribute to its solubility and stability. Overall, the physical properties of 2-Nitro-4-cresol make it an effective antimicrobial agent in various applications such as in cosmetics, pharmaceuticals, and food preservation.
Unfortunately, 2-Nitro-4-cresol and Phenol, 4-methyl-2-nitro- are not skincare ingredients that are commonly used or recommended due to their potential toxicity and harmful effects on the skin. It is important to always research and consult with a skincare professional before using any new ingredient on your skin.
2-Nitro-4-cresol, also known as Phenol, 4-methyl-2-nitro-, is a chemical compound that is commonly used as a preservative in various personal care and cosmetic products. While it is generally considered safe for use in small concentrations, there are some potential side effects, sensitivities, and interactions that should be taken into consideration. One of the main concerns with 2-Nitro-4-cresol is its potential to cause skin irritation and allergic reactions. Some individuals may be more sensitive to this ingredient than others, and may experience symptoms such as redness, itching, and swelling when using products that contain it. In rare cases, more severe reactions such as hives or anaphylaxis may occur. Another potential side effect of 2-Nitro-4-cresol is its ability to cause eye irritation. If this ingredient comes into contact with the eyes, it may cause redness, burning, and watering. In some cases, prolonged exposure to this ingredient may even lead to more serious eye damage. In addition to these potential side effects, there are also some concerns about the interactions that 2-Nitro-4-cresol may have with other ingredients. For example, it is not recommended to use products that contain this ingredient in combination with other preservatives or antimicrobial agents, as this may increase the risk of skin irritation or allergic reactions. Overall, while 2-Nitro-4-cresol is generally considered safe for use in small concentrations, it is important to be aware of the potential side effects, sensitivities, and interactions that may occur. If you experience any adverse reactions when using products that contain this ingredient, it is important to discontinue use and seek medical attention if necessary.
2-Nitro-4-cresol is a synthetic ingredient that is derived from phenol, 4-methyl-2-nitro-. Phenol, 4-methyl-2-nitro- is a synthetic compound that is produced by the nitration of 4-cresol. The nitration process involves the reaction of 4-cresol with a mixture of nitric acid and sulfuric acid. The resulting product is then purified and crystallized to obtain 2-Nitro-4-cresol. This ingredient is commonly used as a preservative in cosmetics and personal care products.
Based on the EWG Skin Deep rating system, 2-Nitro-4-cresol and Phenol, 4-methyl-2-nitro- both have a score of 7, which is considered to be a high hazard. These chemicals are known to be skin irritants and can cause allergic reactions. They are also suspected to be endocrine disruptors and may have harmful effects on the reproductive system. Other sources such as the National Library of Medicine's Hazardous Substances Data Bank also list these chemicals as hazardous and potentially harmful to human health. It is important to use caution when handling products containing these chemicals and to follow proper safety protocols to minimize exposure.
2-Nitro-4-cresol and Phenol, 4-methyl-2-nitro- are both chemical compounds that have potential environmental impacts and ethical sourcing concerns. 2-Nitro-4-cresol is a yellow crystalline solid that is used as a preservative in cosmetics and personal care products. It has been found to be toxic to aquatic organisms and may also be harmful to human health if ingested or inhaled. In addition, the production of 2-nitro-4-cresol may involve the use of hazardous chemicals and energy-intensive processes, which can contribute to environmental pollution and climate change. Phenol, 4-methyl-2-nitro- is a yellow crystalline powder that is used as a dye intermediate and in the production of other chemicals. It has been found to be toxic to aquatic organisms and may also be harmful to human health if ingested or inhaled. The production of phenol, 4-methyl-2-nitro- may also involve the use of hazardous chemicals and energy-intensive processes, which can contribute to environmental pollution and climate change. In terms of ethical sourcing practices, it is important to ensure that these chemicals are produced in a responsible and sustainable manner. This may involve sourcing raw materials from suppliers who adhere to strict environmental and social standards, as well as implementing measures to reduce waste and minimize the use of hazardous chemicals in the production process. Additionally, companies should work to ensure that their products containing these chemicals are safe for consumers and the environment, and that they are properly labeled and disposed of at the end of their useful life.
In conclusion, 2-Nitro-4-cresol, also known as Phenol, 4-methyl-2-nitro-, is a chemical compound commonly used as a preservative in personal care and cosmetic products. While it has been shown to effectively prevent the growth of bacteria and fungi, it also has potential negative effects on human health and the environment. The compound is derived from petroleum and coal tar, which raises concerns about its sustainability. Additionally, its use in products has been restricted in some countries due to safety concerns. Overall, it is important for consumers to be aware of the potential risks associated with this ingredient and to consider alternative, safer preservatives in their personal care products.
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