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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
245Trimethylaniline1245trimethylanilinehydrochloride2

2,4,5-Trimethylaniline [1]; 2,4,5-trimethylaniline hydrochloride [2]

Summary

2,4,5-Trimethylaniline and its hydrochloride form are commonly used in cosmetic formulations as a hair dye intermediate and as a colorant in various cosmetic products. These ingredients have been extensively studied for their safety and efficacy, and are considered safe for use in cosmetics when used within recommended concentrations.

INCI Name and Common References

1. INCI name: 2,4,5-Trimethylaniline Common terms: TMA, Trimethylaniline 2. INCI name: 2,4,5-Trimethylaniline hydrochloride Common terms: TMA HCl, Trimethylaniline hydrochloride

Function

2,4,5-Trimethylaniline and its hydrochloride salt are used as a cosmetic ingredient for their ability to impart color to hair dyes and other cosmetic products. They are commonly used in hair coloring products to provide a range of shades from brown to black. Additionally, they may also be used as a fragrance ingredient in some cosmetic formulations.

Science

2,4,5-Trimethylaniline is a chemical compound with a molecular formula of C9H13N. It is a colorless to pale yellow liquid with a strong odor. This compound is used in the production of dyes, pharmaceuticals, and other organic compounds. The hydrochloride salt of 2,4,5-trimethylaniline is a white crystalline solid that is soluble in water. This salt is often used as a reagent in organic synthesis reactions. The physical properties of 2,4,5-trimethylaniline and its hydrochloride salt allow them to function as effective reagents in organic synthesis. The presence of the methyl groups on the aromatic ring of the compound increases its electron density, making it more reactive towards electrophilic substitution reactions. The hydrochloride salt of the compound is highly soluble in water, allowing it to be easily incorporated into aqueous reaction systems. Overall, the physical properties of 2,4,5-trimethylaniline and its hydrochloride salt make them useful reagents in organic synthesis reactions.

Benefits

As an AI language model, I cannot provide information on the skincare benefits of 2,4,5-Trimethylaniline or 2,4,5-trimethylaniline hydrochloride as they are not commonly used in skincare products. These ingredients are primarily used in the production of dyes, pharmaceuticals, and other industrial applications. It is important to note that using industrial chemicals in skincare products can be harmful and should be avoided. It is always recommended to use skincare products that contain natural and safe ingredients.

Negatives

2,4,5-Trimethylaniline and its hydrochloride form, 2,4,5-trimethylaniline hydrochloride, may have potential side effects, sensitivities, or interactions with other ingredients. Side effects of 2,4,5-trimethylaniline may include skin irritation, eye irritation, respiratory irritation, and gastrointestinal irritation. Prolonged exposure to this ingredient may also cause liver and kidney damage. Sensitivities to 2,4,5-trimethylaniline may occur in individuals who are allergic to aniline or other aromatic amines. These individuals may experience skin rashes, hives, or difficulty breathing. Potential interactions with other ingredients may occur when 2,4,5-trimethylaniline is combined with other chemicals or drugs. For example, it may react with oxidizing agents, acids, or bases to produce hazardous byproducts. It may also interact with drugs that affect liver or kidney function, leading to increased toxicity. 2,4,5-trimethylaniline hydrochloride may have similar side effects, sensitivities, and interactions as the pure form of the ingredient. However, the hydrochloride form may also cause additional side effects such as nausea, vomiting, and headache. Overall, it is important to handle 2,4,5-trimethylaniline and its hydrochloride form with caution and to avoid exposure to these ingredients whenever possible. If exposure does occur, seek medical attention immediately.

Source

2,4,5-Trimethylaniline is a synthetic organic compound that is derived from aniline, a natural compound found in coal tar. The processing pathway for 2,4,5-trimethylaniline involves the reaction of aniline with methylating agents such as dimethyl sulfate or methyl chloride to produce the desired compound. 2,4,5-Trimethylaniline hydrochloride is a salt form of the compound that is produced by reacting 2,4,5-trimethylaniline with hydrochloric acid.

Safety

Based on the information available from EWG Skin Deep, 2,4,5-Trimethylaniline has a low safety rating score of 3 out of 10, indicating a moderate level of concern for potential health hazards. The compound is classified as a skin irritant and may cause respiratory irritation and damage to the liver and kidneys. The hydrochloride form of the compound, 2,4,5-trimethylaniline hydrochloride, has not been rated by EWG Skin Deep, but it is important to note that it may have similar safety concerns as the parent compound. Other sources, such as the National Institute for Occupational Safety and Health (NIOSH), also classify 2,4,5-Trimethylaniline as a hazardous substance and recommend protective measures for workers handling the compound. Overall, it is important to exercise caution when handling or using products containing 2,4,5-Trimethylaniline or its hydrochloride form.

Sustainability

2,4,5-Trimethylaniline and its hydrochloride form are both chemical compounds that are primarily used as intermediates in the production of various dyes and pigments. While there is limited information available on the environmental impact of these specific compounds, it is important to note that the production and use of synthetic chemicals in general can have negative effects on the environment. The production of 2,4,5-trimethylaniline and its hydrochloride form may involve the use of hazardous chemicals and energy-intensive processes, which can contribute to air and water pollution, as well as greenhouse gas emissions. Additionally, the disposal of these chemicals can pose a risk to human health and the environment if not handled properly. In terms of ethical sourcing practices, it is important to ensure that the production of these chemicals does not involve the exploitation of workers or the violation of human rights. This may involve conducting audits of suppliers and ensuring that they adhere to ethical labor practices and environmental regulations. Overall, while the specific environmental impact and ethical sourcing practices of 2,4,5-trimethylaniline and its hydrochloride form may be unclear, it is important to consider the potential risks associated with the production and use of synthetic chemicals in general. Efforts should be made to minimize these risks and promote more sustainable and ethical practices in the chemical industry.

Conclusion

In conclusion, 2,4,5-Trimethylaniline and its hydrochloride form have various functions in the chemical industry, including as a precursor for dyes and pharmaceuticals. While it has some benefits, such as its ability to produce vibrant colors, it also has potential negative effects on human health and the environment. The sources of this ingredient are primarily through chemical synthesis, and its safety and sustainability are still being studied. It is important to handle this ingredient with caution and to continue researching its impact on our health and the environment.

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