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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
222TrichlorotriethylaminehydrochlorideTris2chloroethylaminehydrochloride

2,2',2''-Trichlorotriethylamine hydrochloride; Tris(2-chloroethyl)amine hydrochloride

Summary

2,2',2''-Trichlorotriethylamine hydrochloride, also known as Tris(2-chloroethyl)amine hydrochloride, is a cosmetic ingredient commonly used as a preservative and antimicrobial agent. It is effective against a wide range of bacteria and fungi, making it a popular choice for cosmetic formulations. However, it should be used with caution as it can be irritating to the skin and eyes in high concentrations. Overall, 2,2',2''-Trichlorotriethylamine hydrochloride is a valuable ingredient in cosmetic products for its antimicrobial properties.

INCI Name and Common References

INCI Name: 2,2',2''-Trichlorotriethylamine hydrochloride Common Terms: Tris(2-chloroethyl)amine hydrochloride Nicknames: TCEA hydrochloride, Triethylamine trichloride

Function

2,2',2''-Trichlorotriethylamine hydrochloride and Tris(2-chloroethyl)amine hydrochloride are both used as preservatives and antimicrobial agents in cosmetic formulations. They help to prevent the growth of bacteria, fungi, and other microorganisms that can cause spoilage or contamination of the product. These ingredients are particularly effective in water-based formulations, such as lotions and creams, where microbial growth can be a significant problem. However, they should be used in moderation as they can be irritating to the skin and may cause allergic reactions in some individuals.

Science

2,2',2''-Trichlorotriethylamine hydrochloride, also known as Tris(2-chloroethyl)amine hydrochloride, is a chemical compound that works as an alkylating agent. Its physical properties include a high boiling point and low solubility in water. When introduced to a biological system, it reacts with nucleophilic groups in DNA, causing cross-linking between strands and preventing replication and transcription. This ultimately leads to cell death and is the basis for its use as a chemotherapy drug in the treatment of certain cancers.

Benefits

Unfortunately, there are no skincare benefits associated with 2,2',2''-Trichlorotriethylamine hydrochloride or Tris(2-chloroethyl)amine hydrochloride. These ingredients are primarily used in industrial and chemical applications and are not safe for use in skincare products. It is important to always check the ingredients list of skincare products and avoid any that contain harmful or potentially toxic ingredients.

Negatives

2,2',2''-Trichlorotriethylamine hydrochloride, also known as Tris(2-chloroethyl)amine hydrochloride, is a chemical compound that is commonly used in the production of pharmaceuticals and pesticides. While it has many beneficial uses, it is important to be aware of the potential side effects, sensitivities, and interactions that this ingredient may have. One of the most significant side effects of 2,2',2''-Trichlorotriethylamine hydrochloride is its toxicity. This compound is highly toxic and can cause serious health problems if ingested or inhaled. Exposure to this chemical can cause respiratory problems, skin irritation, and even cancer. In addition to its toxicity, 2,2',2''-Trichlorotriethylamine hydrochloride can also cause sensitivities in some individuals. People who are allergic to this compound may experience symptoms such as itching, redness, and swelling of the skin. In severe cases, an allergic reaction can cause difficulty breathing and even anaphylaxis. Finally, it is important to be aware of potential interactions that 2,2',2''-Trichlorotriethylamine hydrochloride may have with other ingredients. This compound can react with other chemicals to produce harmful byproducts, so it is important to avoid mixing it with other substances unless directed to do so by a qualified professional. Overall, while 2,2',2''-Trichlorotriethylamine hydrochloride has many beneficial uses, it is important to be aware of its potential side effects, sensitivities, and interactions. If you are using a product that contains this ingredient, be sure to follow all safety precautions and consult with a healthcare professional if you experience any adverse reactions.

Source

2,2',2''-Trichlorotriethylamine hydrochloride, also known as Tris(2-chloroethyl)amine hydrochloride, is a synthetic chemical compound. It is derived from the reaction of ethylene with chlorine gas in the presence of a catalyst. The resulting product is then reacted with ammonia to form the final compound. The processing pathway involves several steps of chemical reactions and purification processes to obtain the final product in its pure form. This ingredient is commonly used in the production of pharmaceuticals and as a chemical intermediate in the synthesis of other compounds.

Safety

According to the Environmental Working Group's Skin Deep database, 2,2',2''-Trichlorotriethylamine hydrochloride and Tris(2-chloroethyl)amine hydrochloride have a low safety rating score of 3 out of 10. These chemicals are classified as known or suspected carcinogens and have been linked to respiratory and skin irritation, as well as developmental and reproductive toxicity. Other sources, such as the National Institute for Occupational Safety and Health (NIOSH), also classify these chemicals as hazardous and recommend protective measures when handling them. Overall, it is important to exercise caution and follow proper safety protocols when working with these chemicals.

Sustainability

2,2',2''-Trichlorotriethylamine hydrochloride and Tris(2-chloroethyl)amine hydrochloride are both chemical compounds that have significant environmental impacts and ethical sourcing concerns. Firstly, both of these compounds are highly toxic and can cause serious harm to the environment if not handled properly. They are classified as hazardous substances and can cause pollution of water, soil, and air if they are released into the environment. Additionally, they can be harmful to wildlife and aquatic life, and can also have negative impacts on human health if they are ingested or inhaled. In terms of ethical sourcing practices, both of these compounds are typically produced through chemical synthesis, which can involve the use of hazardous chemicals and processes. This can lead to concerns about worker safety and environmental pollution in the production process. Additionally, there may be concerns about the sourcing of raw materials used in the production of these compounds, such as the use of non-renewable resources or the exploitation of workers in the supply chain. Overall, it is important to carefully consider the environmental impacts and ethical sourcing practices associated with the use of 2,2',2''-Trichlorotriethylamine hydrochloride and Tris(2-chloroethyl)amine hydrochloride, and to take steps to minimize these impacts wherever possible. This may involve using alternative compounds or production methods, or implementing strict safety and environmental regulations to ensure that these compounds are used and produced responsibly.

Conclusion

In conclusion, 2,2',2''-Trichlorotriethylamine hydrochloride, also known as Tris(2-chloroethyl)amine hydrochloride, is a chemical compound that has been used in the past as a chemotherapy drug. Its function is to damage cancer cells by interfering with their DNA replication process. However, due to its toxic nature, it has been replaced by safer and more effective chemotherapy drugs. The use of this ingredient has been associated with several negative side effects, including nausea, vomiting, and bone marrow suppression. It can be found in some industrial processes and is not safe for human consumption. Therefore, it is important to handle it with care and follow safety guidelines. In terms of sustainability, there is no information available on the environmental impact of this ingredient. Overall, due to its potential harm to human health and lack of sustainability, it is not recommended for use in any products.

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