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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
1R4S5R8S12341010Hexachloro67epoxy144a56788aoctahydro1458dimethanonaphthaleneendrinISO

(1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalene (endrin - ISO)

Summary

Endrin (ISO) is a cosmetic ingredient that belongs to the family of hexachlorocyclohexane compounds. It is a colorless, crystalline solid that is used as a pesticide and insecticide. In cosmetics, endrin is used as a preservative and antimicrobial agent. It has been shown to have low toxicity and is considered safe for use in cosmetic products. However, due to its potential environmental impact, its use is restricted in many countries.

INCI Name and Common References

INCI name: Hexachlorocyclopentadiene (and) Endrin (and) Epoxide Common terms: Endrin, Hexachlorocyclopentadiene, Epoxide Nicknames: None commonly used

Function

Endrin is a pesticide and is not typically used as an ingredient in cosmetic formulations. Its use in cosmetics is prohibited by regulatory agencies due to its potential toxicity and harmful effects on human health.

Science

Endrin is a highly toxic insecticide that works by disrupting the nervous system of insects. Its physical properties, including its high lipophilicity and stability, allow it to persist in the environment and accumulate in the fatty tissues of organisms. Once ingested or absorbed, endrin binds to specific receptors in the nervous system, causing hyperexcitation and convulsions that ultimately lead to paralysis and death. Its complex molecular structure, which includes a cyclic epoxide and multiple chlorine atoms, enhances its potency and persistence, making it a highly effective but dangerous pesticide.

Benefits

There are no skincare benefits associated with this ingredient. In fact, it is a highly toxic pesticide that is banned in many countries due to its harmful effects on human health and the environment. It should not be used in any skincare products.

Negatives

Endrin is a highly toxic and persistent organic pollutant that has been banned in many countries due to its harmful effects on human health and the environment. Exposure to endrin can cause a range of side effects, including nausea, vomiting, abdominal pain, dizziness, headache, tremors, convulsions, and even death in severe cases. Endrin is also known to be highly sensitizing to the skin and eyes, and can cause severe irritation, redness, and swelling upon contact. In addition, endrin can interact with other chemicals and ingredients to produce toxic or harmful effects, particularly in combination with other pesticides or insecticides. Due to its toxicity and potential for harm, endrin should be handled with extreme caution and only used in accordance with strict safety guidelines and regulations. Individuals who are exposed to endrin should seek medical attention immediately and take steps to minimize further exposure.

Source

Endrin is a synthetic organic compound that was first synthesized in the 1950s as an insecticide. It is derived from naphthalene and is a chlorinated hydrocarbon. Endrin is not found naturally in the environment. The processing pathway of endrin involves several steps. First, naphthalene is chlorinated to form hexachloronaphthalene. This compound is then epoxidized to form hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalene. Finally, this compound is hydrogenated to form endrin. The resulting product is a white crystalline solid that is highly toxic to a wide range of organisms, including humans. Due to its toxicity, endrin has been banned in many countries.

Safety

According to the Environmental Working Group's Skin Deep database, endrin has a score of 8 out of 10, indicating a high hazard level. The International Agency for Research on Cancer (IARC) has classified endrin as a Group 2B carcinogen, meaning it is possibly carcinogenic to humans. The United States Environmental Protection Agency (EPA) has also classified endrin as a Group B2 probable human carcinogen. Overall, endrin is considered to be a highly toxic and potentially dangerous chemical, and caution should be exercised when handling or using products containing this substance.

Sustainability

Endrin is a highly toxic pesticide that has been banned in many countries due to its severe environmental impact and health risks. It is a persistent organic pollutant that can remain in the environment for decades, contaminating soil, water, and wildlife. Endrin has been linked to a range of health problems, including cancer, reproductive and developmental disorders, and neurological damage. The production and use of endrin have been associated with unethical practices, including the exploitation of vulnerable communities and the violation of human rights. Many of the workers involved in the production and application of endrin have been exposed to high levels of the chemical, leading to serious health problems and even death. Due to its harmful effects on the environment and human health, endrin is no longer used in most countries. However, it is still present in some areas where it was previously used, and its impact continues to be felt. Efforts are underway to clean up contaminated sites and prevent further exposure to this dangerous chemical. In addition, there is a growing movement towards more sustainable and ethical practices in agriculture, including the use of organic and natural pest control methods that do not rely on toxic chemicals like endrin.

Conclusion

In conclusion, endrin is a highly toxic pesticide that has been banned in many countries due to its harmful effects on human health and the environment. While it was once widely used for its effectiveness in controlling pests, its negative impacts outweigh its benefits. Endrin can be found in contaminated soil and water sources, posing a risk to wildlife and human populations. It is important to prioritize the use of safer and more sustainable alternatives to endrin in order to protect our health and the environment.

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