MitoSkin

Longevity Lotion

Sun Protecting

Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
1HIndole23Dione

1H-Indole-2,3-Dione

Summary

1H-Indole-2,3-Dione is a cosmetic ingredient that is commonly used in skincare and haircare products. It is a yellow crystalline powder that is known for its antioxidant and anti-inflammatory properties. This ingredient is often used to help protect the skin from environmental stressors and to promote a more youthful appearance. Additionally, it can help to improve the texture and overall health of the hair. 1H-Indole-2,3-Dione is considered safe for use in cosmetic products and is a popular choice among formulators looking to create effective and high-quality skincare and haircare products.

INCI Name and Common References

INCI Name: 1H-Indole-2,3-Dione Common Terms: Indigo-2,3-Dione, Isatin Nicknames: None

Function

1H-Indole-2,3-Dione is a cosmetic ingredient that plays a role as a colorant and a fragrance agent in cosmetic formulations. It is commonly used in hair dyes, nail polishes, and perfumes to provide a deep, rich color and a pleasant scent. Additionally, it may also have antioxidant properties that can help protect the skin from damage caused by free radicals.

Science

1H-Indole-2,3-Dione, also known as isatin, is a yellow crystalline solid with a melting point of 201-203°C. It is a heterocyclic organic compound that contains both a carbonyl group and an imine group. Isatin has been found to have a variety of biological activities, including antitumor, antiviral, and antibacterial properties. Isatin works by interacting with various enzymes and proteins in the body. For example, it has been shown to inhibit the activity of certain enzymes involved in cancer cell growth and proliferation. Isatin has also been found to inhibit the replication of certain viruses, such as HIV and herpes simplex virus. The physical properties of isatin, such as its carbonyl and imine groups, allow it to form hydrogen bonds and other interactions with biological molecules. These interactions can disrupt the normal function of enzymes and proteins, leading to the observed biological effects of isatin.

Benefits

There is limited research on the skincare benefits of 1H-Indole-2,3-Dione. However, it is known to have antioxidant properties that may help protect the skin from damage caused by free radicals. It may also have anti-inflammatory effects that could potentially reduce redness and irritation. Further studies are needed to fully understand the potential skincare benefits of this ingredient.

Negatives

1H-Indole-2,3-Dione, also known as isatin, is a chemical compound that is commonly used in the pharmaceutical industry as a starting material for the synthesis of various drugs. While it is generally considered safe for use, there are some potential side effects, sensitivities, and interactions that should be taken into consideration. One of the main side effects of isatin is its potential to cause skin irritation and allergic reactions. This is particularly true for individuals who have sensitive skin or who are prone to allergies. If you experience any redness, itching, or swelling after using a product that contains isatin, you should discontinue use immediately and seek medical attention if necessary. Isatin may also interact with other ingredients in certain medications, particularly those that are used to treat depression or anxiety. This is because isatin has been shown to have some antidepressant and anxiolytic properties, and may enhance the effects of these medications. If you are taking any prescription medications, it is important to speak with your doctor before using any products that contain isatin. Finally, it is worth noting that isatin may have some potential interactions with other chemicals or compounds that are commonly found in cosmetics and personal care products. For example, isatin may react with certain preservatives or fragrances, leading to the formation of potentially harmful byproducts. If you are concerned about the safety of any product that contains isatin, it is always best to consult with a healthcare professional or a qualified cosmetic chemist.

Source

1H-Indole-2,3-Dione, also known as isatin, is a synthetic organic compound. It is derived from indole, a natural organic compound found in plants and animals. The processing pathway for isatin involves the oxidation of indole using various chemical reagents such as potassium permanganate or nitric acid. The resulting product is then treated with sulfuric acid to form isatin. Isatin is commonly used in the production of pharmaceuticals and dyes.

Safety

The safety rating score of 1H-Indole-2,3-Dione varies depending on the rating system used. According to the Environmental Working Group's Skin Deep database, this ingredient has a moderate hazard rating of 5 out of 10, indicating that it may have some potential health concerns. Other sources, such as the European Chemicals Agency, classify 1H-Indole-2,3-Dione as a low-risk substance with no significant safety concerns. Overall, it is important to consider multiple sources and factors when assessing the safety of any ingredient.

Sustainability

1H-Indole-2,3-Dione, also known as isatin, is a chemical compound that is commonly used in the production of pharmaceuticals, dyes, and other industrial products. While there is limited information available on the environmental impact of isatin, it is known to be toxic to aquatic organisms and may have negative effects on soil and plant life if released into the environment. In terms of ethical sourcing practices, it is important to ensure that isatin is produced in a responsible and sustainable manner. This may involve sourcing the compound from suppliers who prioritize environmental stewardship and social responsibility, and who adhere to strict safety and quality standards in their production processes. Additionally, it is important to consider the potential impacts of isatin on human health and safety. Exposure to high levels of the compound may cause skin and eye irritation, respiratory problems, and other health issues. Therefore, it is important to handle and use isatin with care, and to follow all relevant safety guidelines and regulations.

Conclusion

In conclusion, 1H-Indole-2,3-Dione is a versatile ingredient with various functions in the pharmaceutical, cosmetic, and food industries. Its scientific properties make it useful in the synthesis of various compounds, and it has been found to have antioxidant and anti-inflammatory benefits. However, its potential negative effects on human health and the environment require further research. It can be sourced from natural and synthetic sources, and its safety and sustainability depend on the specific application and production methods used. Overall, 1H-Indole-2,3-Dione has potential benefits but requires careful consideration and evaluation for safe and sustainable use.

Leave a Message

Chronic skin issues? Contact us for holistic advice.

powerhouse@mitoskin.org

Copyright 2023 MITOSKIN LLC