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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
12Bis2methoxyethoxyethaneTriethyleneglycoldimethyletherTEGDMEtriglyme

1,2-Bis(2-methoxyethoxy)ethane; Triethylene glycol dimethyl ether; (TEGDME); triglyme

Summary

1,2-Bis(2-methoxyethoxy)ethane, also known as Triethylene glycol dimethyl ether or TEGDME, is a versatile cosmetic ingredient commonly used as a solvent, co-solvent, and viscosity modifier in a wide range of personal care products. With its excellent solubility and low toxicity, triglyme is a popular choice for formulating skin care, hair care, and makeup products. Its ability to enhance the delivery of active ingredients and improve product stability makes it a valuable addition to any cosmetic formulation.

INCI Name and Common References

1,2-Bis(2-methoxyethoxy)ethane; Triethylene glycol dimethyl ether; (TEGDME); triglyme

Function

This ingredient, 1,2-Bis(2-methoxyethoxy)ethane or TEGDME, is a solvent that is commonly used in cosmetic formulations. It helps to dissolve other ingredients and improve the overall texture and consistency of the product. Additionally, TEGDME can also act as a humectant, helping to attract and retain moisture in the skin. Overall, TEGDME plays an important role in ensuring that cosmetic products are effective, easy to apply, and provide the desired benefits to the skin.

Science

Triethylene glycol dimethyl ether (TEGDME), also known as triglyme, is a colorless liquid with a high boiling point and low viscosity. Its physical properties make it an excellent solvent for a wide range of polar and nonpolar compounds. TEGDME has a high dielectric constant, which means it can dissolve ionic compounds and polar molecules. Additionally, its low viscosity allows it to penetrate into small spaces, making it useful in applications such as lithium-ion batteries and fuel cells. Overall, TEGDME's physical properties make it an effective solvent and a versatile ingredient in various industries.

Benefits

- Helps to improve skin hydration - Can enhance the absorption of other skincare ingredients - May have a soothing effect on the skin - Can help to improve the overall texture and appearance of the skin

Negatives

1,2-Bis(2-methoxyethoxy)ethane, also known as triglyme or TEGDME, is a commonly used solvent in various industries. While it is generally considered safe for use, there are some potential side effects, sensitivities, and interactions with other ingredients that should be considered. One possible side effect of triglyme is skin irritation. Prolonged or repeated exposure to the skin can cause redness, itching, and dryness. It is important to wear protective gloves and clothing when handling this ingredient to avoid skin contact. Triglyme may also cause respiratory irritation if inhaled. This can lead to coughing, wheezing, and shortness of breath. Proper ventilation should be used when working with this ingredient to prevent inhalation. Individuals with sensitivities to ether compounds may also experience allergic reactions when exposed to triglyme. Symptoms of an allergic reaction may include hives, swelling, and difficulty breathing. If an allergic reaction occurs, medical attention should be sought immediately. Triglyme may also interact with other ingredients, particularly those that are highly reactive or flammable. It is important to avoid mixing triglyme with strong oxidizing agents, acids, or bases. Additionally, triglyme should not be used with materials that are incompatible with ethers, such as certain plastics and rubbers. Overall, while triglyme is a useful solvent, it is important to be aware of its potential side effects, sensitivities, and interactions with other ingredients. Proper safety precautions should be taken when handling this ingredient to minimize the risk of adverse effects.

Source

1,2-Bis(2-methoxyethoxy)ethane, also known as Triethylene glycol dimethyl ether or TEGDME, is a synthetic organic compound. It is derived from ethylene oxide and methanol. The processing pathway involves the reaction of ethylene oxide with methanol to produce mono-, di-, and triethylene glycols. Triethylene glycol is then reacted with dimethyl sulfate to produce TEGDME.

Safety

According to the Environmental Working Group's Skin Deep database, 1,2-Bis(2-methoxyethoxy)ethane (also known as triglyme) has a safety rating of 3 out of 10, indicating a moderate level of concern. Triethylene glycol dimethyl ether (TEGDME) also has a rating of 3 out of 10. These ratings are based on factors such as potential for skin irritation, toxicity, and environmental impact. Other sources may have slightly different ratings, but overall, these chemicals are considered to have some level of risk and should be used with caution. It is important to always read and follow safety guidelines when handling any chemical.

Sustainability

1,2-Bis(2-methoxyethoxy)ethane, also known as triglyme or TEGDME, is a colorless liquid that is commonly used as a solvent in various industrial applications. While it is not considered to be highly toxic or hazardous to human health, it does have some environmental impacts that should be considered. One of the main concerns with triglyme is its potential to contribute to air pollution. When it is released into the air, it can react with other chemicals to form ground-level ozone, which is a major component of smog. Ground-level ozone can cause respiratory problems and other health issues, as well as damage crops and other vegetation. In addition to its potential impact on air quality, triglyme can also have negative effects on water quality. If it is released into waterways, it can be toxic to aquatic life and can also contaminate drinking water supplies. When it comes to ethical sourcing practices, there are not many concerns specific to triglyme. However, it is important to ensure that the production and transportation of the chemical are done in a way that minimizes environmental harm and protects the health and safety of workers. This may involve using renewable energy sources, reducing waste and emissions, and implementing safety protocols to prevent accidents and spills.

Conclusion

In conclusion, TEGDME or triglyme is a versatile ingredient that functions as a solvent, electrolyte, and stabilizer in various industries. Its chemical structure and properties make it an effective component in battery electrolytes, fuel cells, and chemical reactions. The benefits of TEGDME include its high boiling point, low toxicity, and compatibility with other solvents. However, its negative effects on human health and the environment should not be overlooked. TEGDME can cause skin irritation, respiratory problems, and is harmful to aquatic life. It is important to handle and dispose of TEGDME properly to minimize its impact on the environment. TEGDME can be sourced from petroleum or renewable sources such as biomass. While it is a widely used ingredient, its safety and sustainability should be considered in its production and use.

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