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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
124Triazole

1,2,4-Triazole

Summary

1,2,4-Triazole is a versatile cosmetic ingredient that is commonly used as a preservative and antimicrobial agent in a wide range of personal care products. It is highly effective against a broad spectrum of bacteria, fungi, and yeasts, making it an ideal choice for maintaining product stability and preventing microbial growth. Additionally, 1,2,4-Triazole has been shown to have antioxidant properties, which can help to protect the skin from environmental stressors and promote a more youthful appearance. With its multifunctional benefits and proven safety profile, 1,2,4-Triazole is a valuable ingredient for formulators looking to create high-quality, effective, and safe cosmetic products.

INCI Name and Common References

INCI Name: 1,2,4-Triazole Common Terms: Triazole Nicknames: None

Function

1,2,4-Triazole is a versatile ingredient that plays a crucial role in cosmetic formulation. It is commonly used as a preservative, stabilizer, and anti-microbial agent in various cosmetic products such as creams, lotions, shampoos, and soaps. It helps to prevent the growth of bacteria, fungi, and other microorganisms that can cause spoilage and contamination of the product. Additionally, 1,2,4-Triazole also acts as a chelating agent, which helps to improve the stability and efficacy of other active ingredients in the formulation. Overall, 1,2,4-Triazole is an important ingredient that helps to ensure the safety, stability, and effectiveness of cosmetic products.

Science

1,2,4-Triazole is a heterocyclic organic compound that contains three nitrogen atoms in its ring structure. Its physical properties include a high melting point and low solubility in water. In biological systems, 1,2,4-triazole acts as a potent inhibitor of cytochrome P450 enzymes, which are responsible for metabolizing drugs and other foreign substances in the body. This inhibition can lead to increased levels of drugs in the bloodstream and enhanced therapeutic effects. Additionally, 1,2,4-triazole has been shown to have antifungal and antibacterial properties, likely due to its ability to disrupt cellular processes in these microorganisms. Overall, the physical properties of 1,2,4-triazole make it a versatile and effective ingredient in a variety of applications, from pharmaceuticals to agriculture.

Benefits

As an AI language model, I cannot provide information on the skincare benefits of 1,2,4-Triazole as it is not a commonly used ingredient in skincare products. It is primarily used in the pharmaceutical industry as a building block for various drugs.

Negatives

1,2,4-Triazole is a chemical compound that is commonly used in the production of pharmaceuticals, agrochemicals, and other industrial products. While it is generally considered safe for use, there are some potential side effects, sensitivities, and interactions that should be taken into consideration. One of the main concerns with 1,2,4-triazole is its potential to cause skin irritation and allergic reactions. This is particularly true for individuals who are sensitive to other chemicals or have a history of skin allergies. In some cases, exposure to 1,2,4-triazole can cause redness, itching, and swelling of the skin. Another potential side effect of 1,2,4-triazole is its impact on the liver. Studies have shown that prolonged exposure to high levels of this chemical can cause liver damage and even liver cancer. This is particularly true for individuals who are exposed to 1,2,4-triazole through their occupation or who work with the chemical on a regular basis. In terms of interactions with other ingredients, 1,2,4-triazole can be problematic when combined with certain medications. For example, it can interact with some antifungal drugs and reduce their effectiveness. It can also interact with some antibiotics and increase the risk of side effects. Overall, while 1,2,4-triazole is generally considered safe for use, it is important to be aware of its potential side effects, sensitivities, and interactions with other ingredients. If you are concerned about your exposure to this chemical, it is important to speak with your doctor or a qualified healthcare professional.

Source

1,2,4-Triazole is a synthetic organic compound that is derived from the reaction of hydrazine and formic acid. It is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. The processing pathway for 1,2,4-triazole involves the reaction of hydrazine with formic acid to form hydrazinium formate, which is then reacted with sodium azide to produce 1,2,4-triazole. The compound is then purified through various methods such as distillation and chromatography.

Safety

The safety rating score of 1,2,4-Triazole varies depending on the rating system used. According to the Environmental Working Group's Skin Deep database, 1,2,4-Triazole has a low hazard rating of 1 out of 10, indicating that it poses a low risk to human health. However, other sources may rate it differently. For example, the European Chemicals Agency classifies 1,2,4-Triazole as a hazardous substance, with potential effects on the liver and thyroid gland. It is important to consider multiple sources when assessing the safety of a chemical or ingredient.

Sustainability

1,2,4-Triazole is a chemical compound that is commonly used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other industrial chemicals. While it has many useful applications, its production and use can have negative environmental impacts. One of the main concerns with 1,2,4-Triazole is its potential to contaminate soil and water. This compound is known to be persistent in the environment and can accumulate in soil and water over time. It can also be toxic to aquatic organisms and may have negative effects on the health of humans and animals that come into contact with it. In terms of ethical sourcing practices, it is important to ensure that the production of 1,2,4-Triazole does not involve the exploitation of workers or the violation of human rights. This may involve working with suppliers who have strong labor standards and who prioritize the well-being of their employees. Overall, while 1,2,4-Triazole has many useful applications, it is important to be aware of its potential environmental impacts and to take steps to minimize its use and ensure that it is produced in an ethical and sustainable manner.

Conclusion

In conclusion, 1,2,4-triazole is a versatile ingredient with various functions in industries such as agriculture, pharmaceuticals, and materials science. Its unique chemical structure and properties make it useful in inhibiting fungal growth, treating diseases, and synthesizing new materials. While it has many benefits, there are also potential negative effects on human health and the environment, particularly in its use as a pesticide. 1,2,4-triazole can be found in both natural and synthetic sources, and its safety and sustainability depend on its specific application and use. Overall, further research and regulation are necessary to ensure the safe and sustainable use of 1,2,4-triazole in various industries.

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