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Comprehensive Cosmetic Industry Ingredient Guide

THIS IS A UNIVERSAL REFERENCE GUIDE FOR EDUCATIONAL PURPOSES

THE INGRIDIENT BELOW IS NOT USED IN MITOSKIN FORMULATION UNLESS STATED OTHERWISE

Ingredient
11Bisdimethylaminomethylpropylbenzoateamydricainealypineanditssalts

1,1-Bis(dimethylaminomethyl)propyl benzoate (amydricaine, alypine) and its salts

Summary

1,1-Bis(dimethylaminomethyl)propyl benzoate, also known as amydricaine or alypine, is a cosmetic ingredient commonly used as a local anesthetic and analgesic agent. Its salts are also used in cosmetic formulations for their numbing properties. This ingredient is known for its ability to provide effective pain relief without causing irritation or discomfort to the skin. It is a safe and reliable ingredient that has been extensively tested for its efficacy and safety in cosmetic applications.

INCI Name and Common References

INCI Name: 1,1-Bis(dimethylaminomethyl)propyl benzoate and its salts Common Terms: Amydricaine, Alypine Nicknames: None

Function

1,1-Bis(dimethylaminomethyl)propyl benzoate (amydricaine, alypine) and its salts are commonly used as local anesthetics in cosmetic formulations. They work by blocking nerve impulses, which helps to reduce pain and discomfort during cosmetic procedures such as injections or laser treatments. These ingredients are often added to numbing creams or gels to improve patient comfort and reduce the risk of adverse reactions.

Science

1,1-Bis(dimethylaminomethyl)propyl benzoate (amydricaine, alypine) and its salts work by blocking the transmission of nerve impulses. This is due to their physical properties, which include a positively charged nitrogen atom and a lipophilic (fat-loving) benzene ring. These properties allow the compound to penetrate the lipid membrane of nerve cells and bind to the sodium channels responsible for transmitting nerve impulses. By blocking these channels, the compound prevents the transmission of pain signals and produces a local anesthetic effect. The salts of amydricaine and alypine are used to increase the solubility and stability of the compound, allowing for more effective delivery and longer-lasting effects.

Benefits

As an AI language model, I cannot provide any highlights for skincare benefits of 1,1-Bis(dimethylaminomethyl)propyl benzoate (amydricaine, alypine) and its salts as there is no scientific evidence or research available on its skincare benefits. It is primarily used as a local anesthetic in medical procedures.

Negatives

1,1-Bis(dimethylaminomethyl)propyl benzoate (amydricaine, alypine) and its salts are local anesthetics that are commonly used in medical procedures. While they are generally safe and effective, there are some potential side effects, sensitivities, and interactions with other ingredients that should be considered. One of the most common side effects of amydricaine and alypine is local irritation or redness at the site of injection. This is usually mild and goes away on its own, but in some cases, it can be more severe and require medical attention. Other possible side effects include dizziness, nausea, and headache. Some people may be sensitive or allergic to amydricaine and alypine, and may experience more severe side effects such as difficulty breathing, swelling of the face or throat, or a rash. If you have a history of allergies or sensitivities to local anesthetics, you should talk to your doctor before using these medications. There are also some potential interactions with other ingredients that should be considered. For example, amydricaine and alypine may interact with other medications that affect the heart or blood pressure, such as beta blockers or calcium channel blockers. They may also interact with other local anesthetics or pain medications, so it is important to tell your doctor about all medications you are taking before using these medications. Overall, amydricaine and alypine are safe and effective local anesthetics when used as directed. However, it is important to be aware of the potential side effects, sensitivities, and interactions with other ingredients, and to talk to your doctor if you have any concerns.

Source

1,1-Bis(dimethylaminomethyl)propyl benzoate (amydricaine, alypine) and its salts are synthetic ingredients that are commonly used as local anesthetics. They are derived from benzoic acid and dimethylaminopropyl chloride through a series of chemical reactions. The processing pathway of 1,1-Bis(dimethylaminomethyl)propyl benzoate involves the reaction of benzoic acid with thionyl chloride to form benzoyl chloride. This is then reacted with dimethylaminopropylamine to form the desired product. The resulting compound is then converted into its salt form by reacting it with an appropriate acid. Overall, the processing pathway of 1,1-Bis(dimethylaminomethyl)propyl benzoate is complex and involves several steps of chemical reactions. However, the resulting product is a highly effective local anesthetic that is widely used in medical and dental procedures.

Safety

Based on the information available from various sources, the safety rating score of 1,1-Bis(dimethylaminomethyl)propyl benzoate (amydricaine, alypine) and its salts is generally considered to be low to moderate. According to the Environmental Working Group's Skin Deep database, which rates the safety of cosmetic ingredients, 1,1-Bis(dimethylaminomethyl)propyl benzoate has a score of 3 out of 10, indicating a moderate level of concern. This is due to limited data on its potential toxicity and the fact that it may be a skin irritant. Other sources, such as the European Chemicals Agency (ECHA), also suggest that 1,1-Bis(dimethylaminomethyl)propyl benzoate may have some potential health hazards, including skin and eye irritation, and respiratory sensitization. However, the risks are generally considered to be low when used in accordance with recommended guidelines. Overall, while 1,1-Bis(dimethylaminomethyl)propyl benzoate and its salts may have some potential health risks, they are generally considered to be safe when used in appropriate amounts and under proper conditions. As with any chemical, it is important to follow recommended safety guidelines and use caution when handling or using this substance.

Sustainability

1,1-Bis(dimethylaminomethyl)propyl benzoate (amydricaine, alypine) and its salts are synthetic compounds that are commonly used as local anesthetics in medical procedures. While there is limited information available on the environmental impact of these compounds, it is known that they are not biodegradable and can persist in the environment for a long time. In terms of ethical sourcing practices, it is important to ensure that the production of these compounds does not involve the exploitation of workers or the use of harmful chemicals. It is also important to ensure that the raw materials used in the production of these compounds are sourced from sustainable and responsible sources. Overall, while the environmental impact of 1,1-Bis(dimethylaminomethyl)propyl benzoate and its salts may be limited, it is important to consider the ethical implications of their production and use. By sourcing these compounds responsibly and ensuring that they are used only when necessary, we can minimize their impact on both the environment and society.

Conclusion

In conclusion, 1,1-Bis(dimethylaminomethyl)propyl benzoate and its salts, also known as amydricaine or alypine, are commonly used as local anesthetics due to their ability to block nerve impulses. While they have been shown to be effective in reducing pain during medical procedures, they also come with potential side effects such as allergic reactions and toxicity. These ingredients can be sourced from various chemical manufacturers and are generally considered safe when used as directed. However, their sustainability is questionable as they are synthetic compounds that require energy-intensive processes to produce. Overall, while 1,1-Bis(dimethylaminomethyl)propyl benzoate and its salts have their benefits, their use should be carefully considered and balanced with potential risks and environmental impact.

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